Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra

被引:0
|
作者
Tom N Grammatopoulos
Susan M Jones
Ferogh A Ahmadi
Brian R Hoover
Lawrence D Snell
Jesse Skoch
Vimal V Jhaveri
Andy M Poczobutt
James A Weyhenmeyer
W Michael Zawada
机构
[1] Denver and Health Sciences Center,Division of Clinical Pharmacology and Toxicology, Department of Medicine
[2] Denver and Health Sciences Center,Neuroscience Program, Department of Medicine
[3] University of Colorado at Denver and Health Sciences Center,Department of Pharmacology
[4] University of Illinois,Department of Cell and Structural Biology
关键词
Tyrosine Hydroxylase; Losartan; Ventral Tegmental Area; Angiotensin Converting Enzyme Inhibitor; MPTP Injection;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [11] LPS-induced degeneration of dopaminergic neurons of substantia nigra in rats
    Li, Gang
    Sun, Shenggang
    Cao, Xuebing
    Zhong, Jiangxin
    Tong, E'Tang
    Journal of Huazhong University of Science and Technology - Medical Science, 2004, 24 (01): : 83 - 86
  • [12] LPS-induced degeneration of dopaminergic neurons of substantia nigra in rats
    Li Gang
    Sun Shenggang
    Cao Xuebing
    Zhong Jiangxin
    Tong E'tang
    Current Medical Science, 2004, 24 (1) : 83 - 86
  • [13] Meloxicam reduces lipopolysaccharide-induced degeneration of dopaminergic neurons in the rat substantia nigra pars compacta
    Sui, Yi
    Stanic, Davor
    Tomas, Doris
    Jarrott, Bevyn
    Horne, Malcolm K.
    NEUROSCIENCE LETTERS, 2009, 460 (02) : 121 - 125
  • [14] Peripheral iron dextran induced degeneration of dopaminergic neurons in rat substantia nigra
    Jiang, Hong
    Song, Ning
    Wang, Jun
    Ren, Li-Ying
    Xie, Jun-Xia
    NEUROCHEMISTRY INTERNATIONAL, 2007, 51 (01) : 32 - 36
  • [15] Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress
    Xiao-chun Chen
    Yi-can Zhou
    Ying Chen
    Yuan-gui Zhu
    Fang Fang
    Li-min Chen
    Acta Pharmacologica Sinica, 2005, 26 : 56 - 62
  • [16] LPS0induced Degeneration of Dopaminergic Neurons of Substantia Nigra in Rats
    黎钢
    孙圣刚
    曹学兵
    钟建新
    童萼塘
    Current Medical Science, 2004, (01) : 83 - 86
  • [17] Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress
    Chen, XC
    Zhou, YC
    Chen, Y
    Zhu, YG
    Fang, F
    Chen, LM
    ACTA PHARMACOLOGICA SINICA, 2005, 26 (01) : 56 - 62
  • [18] NMDA ANTAGONISM AND PROTECTION OF SUBSTANTIA-NIGRA NEURONS FROM MPTP-INDUCED NEURODEGENERATION IN MARMOSETS
    LANGE, KW
    LOSCHMANN, PA
    SOFIC, E
    BURG, M
    HOROWSKI, R
    KALVERAM, KT
    WACHTEL, H
    RIEDERER, P
    JOURNAL OF NEUROCHEMISTRY, 1993, 61 : S138 - S138
  • [19] Protective effect of ginsenoside Rg1 against MPTP-induced apoptosis in mouse substantia nigra neurons
    Chen, XC
    Chen, Y
    Zhu, YG
    Fang, F
    Chen, LM
    ACTA PHARMACOLOGICA SINICA, 2002, 23 (09) : 829 - 834
  • [20] Nicotine, but not cotinine, partially protects dopaminergic neurons against MPTP-induced degeneration in mice
    Parain, K
    Marchand, V
    Dumery, B
    Hirsch, E
    BRAIN RESEARCH, 2001, 890 (02) : 347 - 350