Synthesis of novel 2'-aryl-4'-hydroxy-4',5,5',6-tetrahydro- 2'H,8H-spiro[indolizine-7,3'-thiophen]-8-one derivatives via sulfa-Michael/aldol cascade reactions

被引：0

作者：

Yulin Huang

Guihua Tang

Demin Ren

Ju-Lan Zeng

Xiaofang Li

机构：

[1] Hunan University of Science and Technology,Key Laboratory of Theoretical Organic Chemistry and Functional Molecules, Ministry of Education, School of Chemistry and Chemical Engineering

[2] Changsha University of Science and Technology,School of Chemistry and Food Engineering

来源：

Chemistry of Heterocyclic Compounds | 2020年 / 56卷

关键词：

1,4-dithiane-2,5-diol; 6,7-dihydroindolizin-8(5; )-one; sulfa-Michael/aldol cascade reaction; spiro heterocycle;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The sulfa-Michael/aldol cascade reaction of (E)-7-arylidene-6,7-dihydroindolizin-8(5H)-ones and 1,4-dithiane-2,5-diol afforded novel 2'-aryl-4'-hydroxy-4',5,5',6-tetrahydro-2'H,8H-spiro[indolizine-7,3'-thiophen]-8-ones in low to moderate yields. The structures of all products were characterized thoroughly by NMR, IR, HRMS, together with X-ray crystallographic analysis.

引用

页码：42 / 46

页数：4

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