Bayesian model-based tight clustering for time course data

被引:0
|
作者
Yongsung Joo
George Casella
James Hobert
机构
[1] Dongguk University,Department of Statistics
[2] University of Florida,Department of Statistics
来源
Computational Statistics | 2010年 / 25卷
关键词
Bayesian cluster analysis; Tight clustering; Time course gene expression; Microarray;
D O I
暂无
中图分类号
学科分类号
摘要
Cluster analysis has been widely used to explore thousands of gene expressions from microarray analysis and identify a small number of similar genes (objects) for further detailed biological investigation. However, most clustering algorithms tend to identify loose clusters with too many genes. In this paper, we propose a Bayesian tight clustering method for time course gene expression data, which selects a small number of closely-related genes and constructs tight clusters only with these closely-related genes.
引用
收藏
页码:17 / 38
页数:21
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