Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis

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作者
Mingjia Tan
Jie Xu
Javed Siddiqui
Felix Feng
Yi Sun
机构
[1] Division of Radiation and Cancer Biology,Institute of Translational Medicine
[2] Department of Radiation Oncology,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases
[3] Zhejiang University School of Medicine,Department of Pathology
[4] Zhejiang University,Department of Radiation Oncology
[5] University of Michigan,undefined
[6] University of San Francisco,undefined
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Prostate tumorigenesis; Pten; PHLPP1; DEPTOR; SAG KO; SAG-SCF E3; Ubiquitin ligase;
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