Two New Anti-Tobacco Mosaic Virus Isoindolin-1-Ones from the Leaves of Nicotiana tabacum

被引：0
|
作者：
Li Xu
Tao Zhou
Jian-Duo Zhang
Le-Le Deng
Jia-Rui Jiang
Wen-Wu Yang
Chun-Bo Liu
Wei-Song Kong
Xue-Mei Li
Guang-Yu Yang
Qiu-Fen Hu
Xin Liu
机构：
[1] Technology Center,Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education
[2] China Tobacco Yunnan Industrial Co.,undefined
[3] Ltd.,undefined
[4] Yunnan Minzu University,undefined
来源：
Chemistry of Natural Compounds | 2021年 / 57卷
关键词：
isoindolin-1-ones; anti-tobacco mosaic virus activity;
D O I：
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中图分类号：
学科分类号：
摘要：
Two new isoindolin-1-ones, 6-(3-hydroxypropyl)-2,4-dimethylisoindolin-1-one (1) and 4-(hydroxymethyl)-6-(3-hydroxypropyl)-2-methylisoindolin-1-one (2), were isolated from the leaves of Nicotiana tabacum. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds 1 and 2 exhibited high anti-TMV activities with inhibition rates of 42.3 and 46.2% at the concentration of 20 μM, respectively.
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页码：1047 / 1050
页数：3
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