Allogeneic hematopoietic stem cell transplantation for refractory mycosis fungoides (MF) and Sezary syndrome (SS)

被引：0
|
作者：
Erden Atilla
Pinar Ataca Atilla
Sinem Civriz Bozdag
Meltem Kurt Yuksel
Selami Kocak Toprak
Pervin Topcuoglu
Bengu Nisa Akay
Hatice Sanli
Gunhan Gurman
Muhit Ozcan
机构：
[1] Ankara University,BMT Unit, Department of Hematology, Cebeci Hospital, School of Medicine
[2] Ankara University,Department of Dermatology, School of Medicine
来源：
International Journal of Hematology | 2017年 / 106卷
关键词：
Mycosis fungoides; Sezary syndrome; Allogeneic hematopoietic stem cell transplantation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Cutaneous T cell lymphoma is a heterogeneous group of lymphoproliferative disorders with different clinical behavior and prognosis in which malignant T cells accumulate in the skin. In the relapsed/refractory stage, treatment strategy varies depending on clinical perspective. We retrospectively evaluated advanced stage relapse or refractory mycosis fungoides and Sezary syndrome patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) at our hospital. The overall response rate was 25%, while the disease progressed and relapsed after transplant in 38% of patients. Allo-HSCT may be a reasonable treatment option in the relapsed/refractory stage.
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页码：426 / 430
页数：4
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