Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury

被引:0
|
作者
Hong Fan
Hai-Bin Tang
Zhe Chen
Hu-Qing Wang
Lei Zhang
Yu Jiang
Tao Li
Cai-Feng Yang
Xiao-Ya Wang
Xia Li
Sheng-Xi Wu
Gui-Lian Zhang
机构
[1] The Second Affiliated Hospital of Xi’an Jiaotong University,Department of Neurology
[2] Fourth Military Medical University,Institute of Neurosciences
[3] Xi’an Jiaotong University,Department of Laboratory Medicine, Xi’an Central Hospital
[4] Xi’an Jiaotong University,Xi’an Jiaotong University Health Science Center
[5] The Second Affiliated Hospital of Xi’an Jiaotong University,Department of Nephrology
关键词
Spinal cord injury; Macrophages/microglia; HMGB1; Polarization; RAGE;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Maresin 1 Promotes Inflammatory Resolution, Neuroprotection, and Functional Neurological Recovery After Spinal Cord Injury
    Francos-Quijorna, Isaac
    Santos-Nogueira, Eva
    Gronert, Karsten
    Sullivan, Aaron B.
    Kopp, Marcel A.
    Brommer, Benedikt
    David, Samuel
    Schwab, Jan M.
    Lopez-Vales, Ruben
    JOURNAL OF NEUROSCIENCE, 2017, 37 (48): : 11731 - 11743
  • [32] Maresin 1 promotes inflammatory resolution, neuroprotection and functional neurological recovery after spinal cord injury
    Francos-Quijorna, I.
    Santos Nogueira, E.
    Gronert, K.
    Sullivan, A. B.
    Kopp, M. A.
    Brommer, B.
    Serhan, C. N.
    David, S.
    Schwab, J. M.
    Lopez Vales, R.
    GLIA, 2017, 65 : E458 - E458
  • [33] Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization
    Gu, Guangjin
    Zhu, Bin
    Ren, Jie
    Song, Xiaomeng
    Fan, Baoyou
    Ding, Han
    Shang, Jun
    Wu, Heng
    Li, Junjin
    Wang, Hongda
    Li, Jinze
    Wei, Zhijian
    Feng, Shiqing
    CELL AND BIOSCIENCE, 2023, 13 (01):
  • [34] Analysis of Serum Pro-Inflammatory Cytokine Levels after Rat Spinal Cord Ischemia/Reperfusion Injury and Correlation with Tissue Damage
    Hasturk, Askin
    Atalay, Basar
    Calisaneller, Tarkan
    Ozdemir, Ozgur
    Oruckaptan, Hakan
    Altinors, Nur
    TURKISH NEUROSURGERY, 2009, 19 (04) : 353 - 359
  • [35] Fluvoxamine Confers Neuroprotection via Inhibiting Infiltration of Peripheral Leukocytes and M1 Polarization of Microglia/Macrophages in a Mouse Model of Traumatic Brain Injury
    Shi, Mingming
    Mi, Liang
    Li, Fanjian
    Li, Ying
    Zhou, Yuan
    Chen, Fanglian
    Liu, Liang
    Chai, Yan
    Yang, Weidong
    Zhang, Jianning
    Chen, Xin
    JOURNAL OF NEUROTRAUMA, 2022, 39 (17-18) : 1240 - 1261
  • [36] Blocking SP/NK1R signaling improves spinal cord hemisection by inhibiting the release of pro-inflammatory cytokines in rabbits
    Zheng, Yuehuan
    Wang, Nannan
    Chen, Zhe
    Shi, Liqiang
    Xu, Xiangyang
    JOURNAL OF SPINAL CORD MEDICINE, 2023, 46 (05): : 848 - 858
  • [37] The Contribution of Disulfide-hmgb1 Released During Ischemia-reperfusion Injury to Pro-inflammatory Macrophage Polarization Following Liver Transplantation
    Terry, A. Q.
    Sosa, R. A.
    Rossetti, M.
    Nevarez-Mejia, J.
    Naini, B. V.
    Kaldas, F.
    Groysberg, V.
    Younan, S.
    Busuttil, R.
    Gjertson, D. W.
    Kupiec-Weglinski, J. W.
    Reed, E.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2021, 21 : 560 - 560
  • [38] Aldose Reductase Regulates Microglia/Macrophages Polarization Through the cAMP Response Element-Binding Protein After Spinal Cord Injury in Mice
    Qian Zhang
    Ganlan Bian
    Peng Chen
    Ling Liu
    Caiyong Yu
    Fangfang Liu
    Qian Xue
    Sookja K. Chung
    Bing Song
    Gong Ju
    Jian Wang
    Molecular Neurobiology, 2016, 53 : 662 - 676
  • [39] Aldose Reductase Regulates Microglia/Macrophages Polarization Through the cAMP Response Element-Binding Protein After Spinal Cord Injury in Mice
    Zhang, Qian
    Bian, Ganlan
    Chen, Peng
    Liu, Ling
    Yu, Caiyong
    Liu, Fangfang
    Xue, Qian
    Chung, Sookja K.
    Song, Bing
    Ju, Gong
    Wang, Jian
    MOLECULAR NEUROBIOLOGY, 2016, 53 (01) : 662 - 676
  • [40] Systemic but not local administration of retinoic acid reduces early transcript levels of pro-inflammatory cytokines after experimental spinal cord injury
    van Neerven, S.
    Mey, J.
    Joosten, E. A.
    Steinbusch, H. W.
    van Kleef, M.
    Marcus, M. A. E.
    Deumens, R.
    NEUROSCIENCE LETTERS, 2010, 485 (01) : 21 - 25