High-dose therapy with ropinirole in patients with Parkinson's disease

被引:0
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作者
M. Müngersdorf
U. Sommer
M. Sommer
H. Reichmann
机构
[1] Department of Neurology,
[2] Technical University of Dresden,undefined
[3] Dresden,undefined
[4] and,undefined
[5] Department of Clinical Neurophysiology,undefined
[6] Center for Neurological Medicine,undefined
[7] University of Göttingen,undefined
[8] Göttingen,undefined
[9] Federal Republic of Germany,undefined
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关键词
Keywords: Ropinirole; high-dose therapy; dyskinesias; motor fluctuations; dopamine agonist; Parkinson's disease.;
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摘要
Ropinirole is effective as mono- and combination therapy in PD. Previous studies have used a maximal dose of 24 mg/day; the present study assesses the effect of higher doses (up to 36 mg/day) on patients with motor fluctuations. Outcome measures were changes in the motor function score of the Unified Parkinson's Disease Rating Scale, the duration of dyskinesias and reductions in levodopa dose.
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页码:1309 / 1317
页数:8
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