The authors report the clinical, echocardiographic, and pathologic findings in two patients treated with more than 5 mg of pergolide daily who developed symptomatic severe heart failure due to restrictive valvular disease. They also describe the echocardiographic data of another eight patients taking similar doses of pergolide presenting no clinical signs of heart failure. The findings suggest a possible role of high doses of pergolide in inducing restrictive valvular disease.
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South Korea
Chung, EJ
Yoon, WT
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South Korea
Yoon, WT
Kim, JY
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South Korea
Kim, JY
Lee, WY
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Neurol, Seoul, South Korea