4-Aryl(indol-3-yl)-2-pyrrolidone-3(5)-carboxamides: synthesis and structure

被引：1
|
作者：
Gorodnicheva, N. V. [1 ]
Vasil'eva, O. S. [1 ]
Ostroglyadov, E. S. [1 ]
Baichurin, R. I. [1 ]
Litvinov, I. A. [2 ]
Makarenko, S. V. [1 ]
机构：
[1] Herzen State Pedag Univ Russia, 48 Nab R Moiki, St Petersburg 191186, Russia
[2] Russian Acad Sci, Fed Res Ctr Kazan Sci Ctr, AE Arbuzov Inst Organ & Phys Chem, 8 Ul Akademika Arbuzova, Kazan 420088, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2024年 / 73卷 / 03期
关键词：
racetams; 2-pyrrolidone; 2-pyrrolidone carboxamides; molecular structure; X-ray diffraction analysis; STEREOSELECTIVE-SYNTHESIS; DERIVATIVES;
D O I：
10.1007/s11172-024-4172-3
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The reaction of methyl 4-aryl(indol-3-yl)-2-pyrrolidone-3(5)-carboxylates with ammonia afforded racemic (3R*,4S*)-4-(indol-3-yl)-2-pyrrolidone-3-carboxamides and (4R*,5R*)-4-aryl-2-pyrrolidone-5-carboxamides. The three-dimensional structures of these compounds were determined by X-ray diffraction analysis.
引用
收藏
页码：624 / 633
页数：10
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