Gentamicin ototoxicity induced apoptosis of the vestibular hair cells of guinea pigs

被引：0
|
作者：
T. Nakagawa
H. Yamane
S. Shibata
Y. Nakai
机构：
[1] Yodogawa Christian Hospital,Department of Otorhinolaryngology
[2] Osaka City University Medical School,Department of Otorhinolaryngology
来源：
European Archives of Oto-rhino-laryngology | 1997年 / 254卷
关键词：
Labyrinthine vestibule; Gentamicin-induced apoptosis; Nick-end labelling; Hair cell changes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
To clarify mechanisms of inner ear cell death induced by aminoglycosides, we used an in situ nick-end labelling method to examine guinea pig vestibular epithelia after chronic systemic treatments with gentamicin to produce apoptosis. Such changes occurred in damaged hair cells, suggesting that this process may be crucial for subsequent repair and cell regeneration.
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页码：9 / 14
页数：5
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