Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

被引：0
|
作者：
David T Riglar
Tobias W Giessen
Michael Baym
S Jordan Kerns
Matthew J Niederhuber
Roderick T Bronson
Jonathan W Kotula
Georg K Gerber
Jeffrey C Way
Pamela A Silver
机构：
[1] Harvard Medical School,Department of Systems Biology
[2] Wyss Institute for Biologically Inspired Engineering,Department of Biomedical Informatics
[3] Harvard University,Department of Microbiology and Immunology
[4] Harvard Medical School,Department of Pathology
[5] Harvard Medical School,undefined
[6] Massachusetts Host-Microbiome Center,undefined
[7] Brigham and Women's Hospital,undefined
[8] Harvard Medical School,undefined
[9] Present addresses: Emulate Inc.,undefined
[10] Boston,undefined
[11] Massachusetts,undefined
[12] USA (S.J.K.) and SynLogic,undefined
[13] Cambridge,undefined
[14] Massachusetts,undefined
[15] USA (J.W.K.).,undefined
来源：
Nature Biotechnology | 2017年 / 35卷
关键词：
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学科分类号：
摘要：
An engineered commensal E. coli strain can function as a living diagnostic for a marker of inflammation in the murine gut for 200 days.
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页码：653 / 658
页数：5
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