Correction of Endothelial Dysfunction in Patients with Arterial Hypertension

被引：0
|
作者：
M. A. Soloviev
N. V. Kulakova
T. A. Semiglazova
E. V. Borodulina
V. V. Udut
机构：
[1] Institute of Pharmacology,
[2] Siberian Division of the Russian Academy of Medical Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2011年 / 151卷
关键词：
hypertension; endothelial dysfunction; inflammation; cyclooxygenase-1, -2; non-steroidal anti-inflammatory drugs;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We examined 38 patients (mean age 55.92 ± 1.56 years) with a 3-5-year history of arterial hypertension. The study showed that hypertension is accompanied by endothelial dysfunction and one of its forming factors is activation of the inflammatory response. Highly sensitive diagnostic tests can verify initiation of inflammation in preclinical manifestations. The use of nonsteroidal anti-inflammatory drugs, irrespective of the tropism to cyclooxygenase forms, alleviates manifestations of endothelial dysfunction in patients with arterial hypertension.
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页码：183 / 185
页数：2
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