Understanding the mechanisms and translational implications of the microbiome for cancer therapy innovation

被引：0
|
作者：
Jessica Queen
Fyza Shaikh
Cynthia L. Sears
机构：
[1] Johns Hopkins University School of Medicine,Division of Infectious Diseases, Department of Medicine
[2] Johns Hopkins University School of Medicine,Cancer Immunology Program, Department of Oncology
[3] Bloomberg School of Public Health,Department of Microbiology and Molecular Immunology
来源：
Nature Cancer | 2023年 / 4卷
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摘要：
The intersection of the microbiota and cancer and the mechanisms that define these interactions are a fascinating, rapidly evolving area of cancer biology and therapeutics. Here we present recent insights into the mechanisms by which specific bacteria or their communities contribute to carcinogenesis and discuss the bidirectional interplay between microbiota and host gene or epigenome signaling. We conclude with comments on manipulation of the microbiota for the therapeutic benefit of patients with cancer.
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页码：1083 / 1094
页数：11
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