HPLC separation of opium alkaloids on porous and non-porous stationary phases

被引：0
|
作者：
L. Krenn
B. Boros
R. Ohmacht
L. Jelinek
机构：
[1] University of Vienna,Institute of Pharmacognosy
[2] University Medical School of Pecs,Institute of Medical Chemistry
[3] Chemie Uetikon AG,undefined
来源：
Chromatographia | 2000年 / 51卷
关键词：
Column liquid chromatography; Non-porous stationary phase; Opium alkaloids; Poppy,; L.;
D O I：
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中图分类号：
学科分类号：
摘要：
A new reversed-phase (RP) HPLC method has been developed and validated for the separation of the main opium alkaloids morphine, codeine, thebaine, papaverine and noscapine on a non-porous (micropellicular) stationary phase. On this phase quantification of the compounds by internal standardization with brucine was achieved extremely rapidly, in ca 1.5 min, only. Thus, the analysis time for the opium alkaloids was approximately one tenth of that on porous stationary phases. Different opium samples were investigated using non-porous and porous packings. The correlation between the results was excellent.
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页码：S175 / S178
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