Finite Element Model to Study Calcium Distribution in T Lymphocyte Involving Buffers and Ryanodine Receptors

被引:0
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作者
Hemant Kumar
Parvaiz Ahmad Naik
Kamal Raj Pardasani
机构
[1] Indian Institute of Technology,Department of Mathematics
[2] Islamic University of Science & Technology,Department of Mathematics
[3] Maulana Azad National Institute of Technology,Department of Mathematics
关键词
Finite element method; Buffers; MATLAB; T lymphocytes; Ryanodine receptors (RyRs); Diffusion coefficient; Reaction diffusion equations;
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摘要
In this paper an attempt has been made to develop a mathematical model to study intracellular calcium distribution in T lymphocyte for a one dimensional unsteady state case. The model incorporates the parameters like diffusion coefficient, ryanodine receptors (RyRs), source influx and buffers. The boundary conditions have been framed using biophysical conditions of the problem. The finite element method has been employed to obtain the solution of the proposed mathematical model. The numerical results are used to study relationship between concentration and position with respect to source influx, buffers and ryanodine receptors (RyRs).
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页码:585 / 590
页数:5
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