Extracellular vesicles in coronary artery disease

被引：0
|
作者：
Chantal M. Boulanger
Xavier Loyer
Pierre-Emmanuel Rautou
Nicolas Amabile
机构：
[1] Institut National de la Santé et de la Recherche Médicale (INSERM),Cardiology Department
[2] Unit 970,undefined
[3] Paris Cardiovascular Research Center – PARCC,undefined
[4] Université Paris Descartes,undefined
[5] Sorbonne Paris Cité,undefined
[6] UMR-S970,undefined
[7] Service d'Hépatologie,undefined
[8] DHU Unity Hôpital Beaujon,undefined
[9] APHP,undefined
[10] Université Denis Diderot-Paris 7,undefined
[11] Sorbonne Paris Cité,undefined
[12] Institut Mutualiste Monsouris,undefined
来源：
Nature Reviews Cardiology | 2017年 / 14卷
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摘要：
Extracellular vesicles are released in biological fluids both under basal conditions and in pathological settingsExtracellular vesicles act as vectors of biological information by transferring their protein, lipid, and nucleic acid content to target cellsCirculating levels of extracellular vesicles of different cellular origin are increased in cardiovascular diseases, including myocardial infarction; these extracellular vesicles could serve as diagnostic and prognostic biomarkersExtracellular vesicles might contribute to atherosclerosis development and progression by promoting initial lesion formation, intravascular calcifications, unstable plaque progression, and thrombus formation after ruptureExtracellular vesicles released by stem cells (progenitor or mesenchymal stem cells) have potential therapeutic benefits on cardiac function after myocardial infarction
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页码：259 / 272
页数：13
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