Aliphatic aldehydes in synthesis of 4-alkyl-5-carbamoyl-3-cyano-6-methylpyrtoine-2(1H)-thiones

被引：0

作者：

Krivokolysko S.G. ^{[1
]}

Dyachenko V.D. ^{[1
]}

Litvinov V.P. ^{[2
]}

机构：

[1] Lugansk T. G. Shevchenko State Pedagogical Institute

[2] N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences

来源：

Chemistry of Heterocyclic Compounds | 1999年 / 35卷 / 2期

关键词：

Methyl; Acetic; Bromide; Organic Chemistry; Aldehyde;

D O I：

10.1007/BF02251710

中图分类号：

学科分类号：

摘要：

Condensation of isovaleric or acetic aldehydes with cyanothioacetamide and acetoacetamide leads to formation of 4-isobutyl(methyl)-5-carbamoyl-3-cyano-6-methylpyridine-2(1H)-thiones. By alkylation of 5-carbamoyl-3-cyano-4,6-dimethylpyridine-2(1H)-thione with 4-methoxyphenacyl bromide, 5-carbamoyl-3-cyano-4,6-dimethyl-2-(4-methoxybenzoyl)methylthiopyridine has been obtained. ©1999 KluwerAcademic/Plenum.

引用

页码：204 / 205

页数：1

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