Aliphatic aldehydes in synthesis of 4-alkyl-5-carbamoyl-3-cyano-6-methylpyrtoine-2(1H)-thiones

被引：0
|
作者：
Krivokolysko S.G. [1 ]
Dyachenko V.D. [1 ]
Litvinov V.P. [2 ]
机构：
[1] Lugansk T. G. Shevchenko State Pedagogical Institute
[2] N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences
来源：
Chemistry of Heterocyclic Compounds | 1999年 / 35卷 / 2期
关键词：
Methyl; Acetic; Bromide; Organic Chemistry; Aldehyde;
D O I：
10.1007/BF02251710
中图分类号：
学科分类号：
摘要：
Condensation of isovaleric or acetic aldehydes with cyanothioacetamide and acetoacetamide leads to formation of 4-isobutyl(methyl)-5-carbamoyl-3-cyano-6-methylpyridine-2(1H)-thiones. By alkylation of 5-carbamoyl-3-cyano-4,6-dimethylpyridine-2(1H)-thione with 4-methoxyphenacyl bromide, 5-carbamoyl-3-cyano-4,6-dimethyl-2-(4-methoxybenzoyl)methylthiopyridine has been obtained. ©1999 KluwerAcademic/Plenum.
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页码：204 / 205
页数：1
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