Rolling on N-linked glycans: a new way to present L-selectin binding sites

被引:0
|
作者
Ronen Alon
Steven Rosen
机构
[1] Weizmann Institute of Science,Ronen Alon is in the Department of Immunology
[2] Rehovot,Steven Rosen is in the Department of Anatomy and Program in Immunology
[3] 76100 Israel.,undefined
[4] University of California,undefined
[5] San Francisco,undefined
[6] San Francisco,undefined
[7] California,undefined
[8] 94143-0451,undefined
[9] USA.,undefined
来源
Nature Immunology | 2007年 / 8卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Recruitment of lymphocytes to the lymph nodes requires L-selectin-mediated recognition of carbohydrate determinants presented by O-glycans. New work shows that N-glycans 'decorated' with the same determinants also contribute to lymphocyte homing.
引用
收藏
页码:339 / 341
页数:2
相关论文
共 50 条
  • [41] DISRUPTION OF POTENTIAL SITES FOR N-LINKED GLYCOSYLATION DOES NOT IMPAIR HORMONE BINDING TO THE LUTROPIN CHORIOGONADOTROPIN RECEPTOR IF ASN-173 IS LEFT INTACT
    LIU, XB
    DAVIS, D
    SEGALOFF, DL
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (03) : 1513 - 1516
  • [42] Sensing the interactions between carbohydrate-binding agents and N-linked glycans of SARS-CoV-2 spike glycoprotein using molecular docking and simulation studies
    Lokhande, Kiran Bharat
    Apte, Girish R.
    Shrivastava, Ashish
    Singh, Ashutosh
    Pal, Jayanta K.
    Swamy, K. Venkateswara
    Gupta, Rajesh Kumar
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2022, 40 (09): : 3880 - 3898
  • [43] L-selectin mediated rolling in inflamed venules, but not in Peyer's patch high endothelial venules, is absent in core 2 β-1,6-N-acetylglucosaminyltransferase deficient mice
    Sperandio, M
    Ellies, LG
    Marth, JD
    Ley, K
    FASEB JOURNAL, 2001, 15 (05): : A1179 - A1179
  • [44] THE ROLE OF CALCIUM AND N-LINKED GLYCANS IN THE OLIGOMERIZATION AND CARBOHYDRATE-BINDING PROPERTIES OF HUMAN-IMMUNODEFICIENCY-VIRUS EXTERNAL ENVELOPE GLYCOPROTEIN (VOL 11, PG 73, 1994)
    HAIDAR, M
    SEDDIKI, N
    GLUCKMAN, JC
    GATTEGNO, L
    GLYCOCONJUGATE JOURNAL, 1994, 11 (05) : 500 - 500
  • [45] Recombinant Human Lysyl Oxidase-like 2 Secreted from Human Embryonic Kidney Cells Displays Complex and Acidic Glycans at All Three N-Linked Glycosylation Sites
    Go, Eden P.
    Moon, Hee-Jung
    Mure, Minae
    Desaire, Heather
    JOURNAL OF PROTEOME RESEARCH, 2018, 17 (05) : 1826 - 1832
  • [46] N-linked glycans are required to improve catalytic activity of BjussuSP-I, a new thrombin-like glycoprotein isolated from Bothrops jararacussu snake venom
    Oliveira, Leandro Licursi
    Soares, Sandro Gomes
    Sant'Ana, Carolina Dalaqua
    Sampaio, Suely Vilela
    Soares, Andreimar Martins
    Roque-Barreira, Maria Cristina
    GLYCOBIOLOGY, 2006, 16 (11) : 1128 - 1128
  • [47] Removal of two high-mannose N-linked glycans on gp120 renders human immunodeficiency virus 1 largely resistant to the carbohydrate-binding agent griffithsin
    Huang, Xin
    Jin, Wei
    Griffin, George E.
    Shattock, Robin J.
    Hu, Qinxue
    JOURNAL OF GENERAL VIROLOGY, 2011, 92 : 2367 - 2373
  • [48] Interaction between heat-stable enterotoxin and its receptor (guanylyl cyclase C):: influence of mutation at N-linked glycosylation sites on its ligand binding
    Hasegawa, M
    Matsumoto, Y
    Hidaka, Y
    Shimonishi, Y
    PEPTIDE SCIENCE - PRESENT AND FUTURE, 1999, : 221 - 222
  • [49] Identification of the N-linked glycosylation sites on the high density lipoprotein (HDL) receptor SR-BI and assessment of their effects on HDL binding and selective lipid uptake
    Viñals, M
    Xu, SZ
    Vasile, E
    Krieger, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (07) : 5325 - 5332
  • [50] Synthesis of a new nanomolar saccharide inhibitor of lymphocyte adhesion: Different polylactosamine backbones present multiple sialyl Lewis x determinants to L-selectin in high-affinity mode
    Renkonen, O
    Toppila, S
    Penttila, L
    Salminen, H
    Helin, J
    Maaheimo, H
    Costello, CE
    Turunen, JP
    Renkonen, R
    GLYCOBIOLOGY, 1997, 7 (04) : 453 - 461