Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour–stroma interaction

被引:0
|
作者
T Nagasaki
M Hara
H Nakanishi
H Takahashi
M Sato
H Takeyama
机构
[1] Nagoya City University,Department of Gastroenterological Surgery
[2] 1 Kawasumi,Division of Oncological Pathology
[3] Mizuho-cho,undefined
[4] Mizuho-ku,undefined
[5] Nagoya 467-8601,undefined
[6] Japan,undefined
[7] Aichi Cancer Center Institute,undefined
[8] 1-1 Kanokoden,undefined
[9] Chikusa-ku,undefined
[10] Nagoya 464-8681,undefined
[11] Japan,undefined
来源
British Journal of Cancer | 2014年 / 110卷
关键词
cancer-associated fibroblast (CAF); cancer-stroma interaction (CSI); Interlerukin-6 (IL-6); angiogenesis; VEGF; colon cancer;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:469 / 478
页数:9
相关论文
共 40 条
  • [21] Successful Treatment of Autoimmune Hemolytic Anemia Associated with Multicentric Castleman Disease by Anti-Interleukin-6 Receptor Antibody (Tocilizumab) Therapy
    Yuzuriha, Akinori
    Saitoh, Takayuki
    Koiso, Hiromi
    Mitsui, Takeki
    Uchiumi, Hideki
    Yokohama, Akihiko
    Handa, Hiroshi
    Kojima, Masaru
    Tsukamoto, Norifumi
    Karaswa, Masamitsu
    Murakami, Hirokazu
    Nojima, Yoshihisa
    ACTA HAEMATOLOGICA, 2011, 126 (03) : 147 - 150
  • [22] ANTI-INTERLEUKIN-6 RECEPTOR ANTIBODY (MR16-1) SUPPRESSED COLONIC CARCINOGENESIS IN HIGH FAT DIET INDUCED OBESITY MOUSE
    Matsumoto, Hiroshi
    Fukushima, Shinya
    Goda, Kyosuke
    Katsumata, Ryo
    Murao, Takahisa
    Ishii, Manabu
    Shiotani, Akiko
    GASTROENTEROLOGY, 2018, 154 (06) : S425 - S425
  • [23] Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells
    Cheteh, Emarndeena H.
    Sarne, Victoria
    Ceder, Sophia
    Bianchi, Julie
    Augsten, Martin
    Rundqvist, Helene
    Egevad, Lars
    Ostman, Arne
    Wiman, Klas G.
    CELL DEATH DISCOVERY, 2020, 6 (01)
  • [24] Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells
    Emarndeena H. Cheteh
    Victoria Sarne
    Sophia Ceder
    Julie Bianchi
    Martin Augsten
    Helene Rundqvist
    Lars Egevad
    Arne Östman
    Klas G. Wiman
    Cell Death Discovery, 6
  • [25] Eicosapentaenoic acid suppresses angiogenesis via reducing secretion of IL-6 and VEGF from colon cancer-associated fibroblasts
    Ando, Nanako
    Hara, Masayasu
    Shiga, Kazuyoshi
    Yanagita, Takeshi
    Takasu, Korehito
    Nakai, Nozomu
    Maeda, Yuzo
    Hirokawa, Takahisa
    Takahashi, Hiroki
    Ishiguro, Hideyuki
    Matsuo, Yoichi
    Takiguchi, Shuji
    ONCOLOGY REPORTS, 2019, 42 (01) : 339 - 349
  • [26] Successful treatment of multicentric Castleman's disease associated with dystrophic epidermolysis bullosa using anti-interleukin-6 receptor antibody
    Naruse, Satsuki
    Takashima, Shota
    Fujita, Yasuyuki
    Kataoka, Hiroshi
    Kawamura, Nobuaki
    Natsuga, Ken
    Ujiie, Hideyuki
    JOURNAL OF DERMATOLOGY, 2024, 51 (08): : e268 - e269
  • [27] Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice
    Wallner, L
    Dai, JL
    Escara-Wilke, J
    Zhang, J
    Yao, Z
    Lu, Y
    Trikha, M
    Nemeth, JA
    Zaki, MH
    Keller, ET
    CANCER RESEARCH, 2006, 66 (06) : 3087 - 3095
  • [28] Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis - A randomized, double-blind, placebo-controlled, dose-escalation trial
    Choy, EHS
    Isenberg, DA
    Garrood, T
    Farrow, S
    Ioannou, Y
    Bird, H
    Cheung, N
    Williams, B
    Hazleman, B
    Price, R
    Yoshizaki, K
    Nishimoto, N
    Kishimoto, T
    Panayi, GS
    ARTHRITIS AND RHEUMATISM, 2002, 46 (12): : 3143 - 3150
  • [29] Correlation of interleukin-6 and monocyte chemotactic protein-1 concentrations with crescent formation and myeloperoxidase-specific anti-neutrophil cytoplasmic antibody titer in SCG/Kj mice by treatment with anti-interleukin-6 receptor antibody or mizoribine
    Nagao, Tomokazu
    Kusunoki, Reina
    Iwamura, Chiaki
    Kobayashi, Shigeto
    Yumura, Wako
    Kameoka, Yosuke
    Nakayama, Toshinori
    Suzuki, Kazuo
    MICROBIOLOGY AND IMMUNOLOGY, 2013, 57 (09) : 640 - 650
  • [30] Successful Treatment of a Mesangial Proliferative Glomerulonephritis with Interstitial Nephritis Associated with Castleman's Disease by an Anti-interleukin-6 Receptor Antibody (Tocilizumab)
    Otani, Naoko
    Morishita, Yoshiyuki
    Oh, Iekuni
    Saito, Osamu
    Takemoto, Fumi
    Muto, Shigeaki
    Kusano, Eiji
    INTERNAL MEDICINE, 2012, 51 (11) : 1375 - 1378