Preparation and Antihypoxic Activity of Complexes of Uracil Derivatives with Dicarboxylic Acids

被引：0
|
作者：
A. R. Gimadieva
V. A. Myshkin
A. G. Mustafin
Yu. N. Chernyshenko
N. S. Borisova
Yu. S. Zimin
I. B. Abdrakhmanov
机构：
[1] Ufa Scientific Center,Institute of Organic Chemistry
[2] Russian Academy of Sciences,undefined
[3] Institute of Labor Medicine and Human Ecology,undefined
[4] Bashkir State University,undefined
来源：
Pharmaceutical Chemistry Journal | 2014年 / 48卷
关键词：
6-methyluracil; complexes; dicarboxylic acids; acute toxicity; antihypoxic activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Water-soluble low-toxicity complexes of 6-methyluracil and its derivatives with succinic and fumaric acids were synthesized. The synthesized complexes were tested for antihypoxic activity.
引用
收藏
页码：93 / 96
页数：3
相关论文
共 50 条
  • [41] Adenine and uracil derivatives with antitubercular activity
    Alksnis E.
    Korneeva D.
    Lukevics E.
    Chemistry of Heterocyclic Compounds, 2001, 37 (6) : 743 - 746
  • [42] Inclusion complexes of β-cyclodextrin with some dicarboxylic acids
    G. I. Kurochkina
    D. A. Shipilov
    T. N. Popkova
    T. A. Batalova
    M. K. Grachev
    Russian Journal of Organic Chemistry, 2015, 51 : 918 - 919
  • [43] Improving methodology for the preparation of uracil derivatives from Fischer carbene complexes. Microwave activation
    Spinella, A
    Caruso, T
    Pastore, U
    Ricart, S
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2003, 684 (1-2) : 266 - 268
  • [44] SYNTHESIS, PSYCHOPHARMACOLOGICAL AND ANTIHYPOXIC ACTIVITY OF BETA-SUBSTITUTED PYRIDINECARBOXYLIC ACIDS
    STOLYAROVA, LG
    AKHUNDOV, RA
    RAKHMANKULOVA, IK
    VORONINA, TA
    SMIRNOV, LD
    DYUMAEV, KM
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1986, 20 (01): : 45 - 47
  • [45] Synthesis of uracil derivatives by oxidation of Fischer tungsten-carbene uracil complexes
    Della Sala, Giorgio
    Artillo, Antonietta
    Ricart, Susagna
    Spinella, Aldo
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2007, 692 (08) : 1623 - 1627
  • [46] IDENTIFICATION OF DICARBOXYLIC ACIDS IN POLYMERIC ESTERS - PREPARATION AND PROPERTIES OF THE DIBENZYL AMIDES OF 8 TYPICAL DICARBOXYLIC ACIDS
    STAFFORD, RW
    FRANCEL, RJ
    SHAY, JF
    ANALYTICAL CHEMISTRY, 1949, 21 (12) : 1454 - 1457
  • [47] Energetic characterization of uracil derivatives: Orotic and isoorotic acids
    Amaral, Luisa M. P. F.
    Szterner, Piotr
    Morais, Victor M. F.
    Ribeiro da Sliva, Maria D. M. C.
    Ribeiro da Silva, Manuel A. V.
    THERMOCHIMICA ACTA, 2020, 683
  • [48] The nephropathic action of the dicarboxylic acids and their derivatives II Glutaric and malonic acids
    Rose, WC
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1924, 24 (02): : 147 - 158
  • [49] Multicomponent solids of uracil derivatives - orotic and isoorotic acids
    Kumar, Vineet
    Goswami, Pramod Kumar
    Thaimattam, Ram
    Ramanan, Arunachalam
    CRYSTENGCOMM, 2018, 20 (25): : 3490 - 3504
  • [50] SYNTHESIS AND REDUCTION OF DERIVATIVES OF AZIRIDINEMONOCARBOXYLIC-ACIDS AND DICARBOXYLIC-ACIDS
    TRAPENTSIER, PT
    KALNINSH, IY
    LIEPINSH, EE
    LUKEVITS, E
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1983, (09): : 1227 - 1235
12345