Antigen-presenting cells look within during influenza infection

被引:0
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作者
Justine D Mintern
Jose A Villadangos
机构
[1] Bio21 Molecular Science and Biotechnology Institute,Justine D. Mintern is in the Department of Biochemistry and Molecular Biology
[2] The University of Melbourne,Jose A. Villadangos is in the Department of Biochemistry and Molecular Biology, and in the Department of Microbiology and Immunology
[3] Parkville,undefined
[4] Victoria,undefined
[5] Australia.,undefined
[6] Bio21 Molecular Science and Biotechnology Institute,undefined
[7] Doherty Institute for Infection and Immunity,undefined
[8] The University of Melbourne,undefined
[9] Victoria,undefined
[10] Australia.,undefined
来源
Nature Medicine | 2015年 / 21卷
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摘要
During viral infections, antigen-presenting cells (APC) have traditionally been thought to recruit and activate CD4+ T cells by presenting fragments of viral proteins captured from the extracellular environment. A new study indicates that the material the APCs need to present is much closer: in fact, APCs need to make it themselves.
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页码:1123 / 1125
页数:2
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