Antigen-presenting cells look within during influenza infection

被引：0

作者：

Justine D Mintern

Jose A Villadangos

机构：

[1] Bio21 Molecular Science and Biotechnology Institute,Justine D. Mintern is in the Department of Biochemistry and Molecular Biology

[2] The University of Melbourne,Jose A. Villadangos is in the Department of Biochemistry and Molecular Biology, and in the Department of Microbiology and Immunology

[3] Parkville,undefined

[4] Victoria,undefined

[5] Australia.,undefined

[6] Bio21 Molecular Science and Biotechnology Institute,undefined

[7] Doherty Institute for Infection and Immunity,undefined

[8] The University of Melbourne,undefined

[9] Victoria,undefined

[10] Australia.,undefined

来源：

Nature Medicine | 2015年 / 21卷

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摘要：

During viral infections, antigen-presenting cells (APC) have traditionally been thought to recruit and activate CD4+ T cells by presenting fragments of viral proteins captured from the extracellular environment. A new study indicates that the material the APCs need to present is much closer: in fact, APCs need to make it themselves.

引用

页码：1123 / 1125

页数：2

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