8-O-4′-Neolignans from the Stem Bark of Illicium difengpi and their ANTI-HIV-1 Activities

被引：0
|
作者：
Yuchun Yang
Ying Qin
Yanlin Meng
Congfang Xia
Xuemei Gao
Qiufen Hu
机构：
[1] Yunnan University of Nationalities,Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education
来源：
Chemistry of Natural Compounds | 2016年 / 52卷
关键词：
8-; -4′-neolignans; anti-HIV-1 activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two new 8-O-4′-neolignans, difenneolignans A and B (1and2), together with six known neolignans (3–8), were isolated from the stem bark of Illicium difengpi. The structures of1–8were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds1and2were also tested for their anti-HIV-1 activities. The results revealed significant activities for compounds1and2with therapeutic index (TI) values of 95.5 and 114.4, respectively.
引用
下载
收藏
页码：43 / 47
页数：4
相关论文
共 50 条
  • [41] Cytotoxic and anti-HIV-1 activities of triterpenoids and flavonoids isolated from leaves and twigs of Gardenia sessiliflora
    Thanasansurapong, Sariyarach
    Tuchinda, Patoomratana
    Reutrakul, Vichai
    Pohmakotr, Manat
    Piyachaturawat, Pawinee
    Chairoungdua, Arthit
    Suksen, Kanoknetr
    Akkarawongsapat, Radeekorn
    Limthongkul, Jitra
    Napaswad, Chanita
    Nuntasaen, Narong
    PHYTOCHEMISTRY LETTERS, 2020, 35 : 46 - 52
  • [42] Anti-HIV-1 activity of phlorotannin derivative 8,4′′′-dieckol from Korean brown alga Ecklonia cava
    Karadeniz, Fatih
    Kang, Kyong-Hwa
    Park, Jae W.
    Park, Sun-Joo
    Kim, Se-Kwon
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2014, 78 (07) : 1151 - 1158
  • [43] Water-soluble Phenolic Compounds and Their Anti-HIV-1 Activities from the Leaves of Cyclocarya paliurus
    Zhang, Juan
    Huang, Ning
    Lu, Jin-Cai
    Li, Xu
    Wang, Yun-Hua
    Yang, Liu-Meng
    Zheng, Yong-Tang
    Xiao, Kai
    JOURNAL OF FOOD AND DRUG ANALYSIS, 2010, 18 (06) : 398 - 404
  • [44] Two new 8-O-4′-type lignans from the stem of Schima superba and their cell growth inhibitory activities against human cancer cell lines
    Xu, Wen
    Wang, Hui
    Zhou, Guang-Xiong
    Yao, Xin-Sheng
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2010, 12 (10) : 874 - 878
  • [45] Anti-HIV-1 reverse transcriptase activities of hexane extracts from some Asian medicinal plants
    Silprasit, Kun
    Seetaha, Supaporn
    Pongsanarakul, Parinya
    Hannongbua, Supa
    Choowongkomon, Kiattawee
    JOURNAL OF MEDICINAL PLANTS RESEARCH, 2011, 5 (17): : 4194 - 4201
  • [46] Evaluation of Anti-HIV-1 Integrase and Anti-Inflammatory Activities of Compounds from Betula alnoides Buch-Ham
    Chaniad, Prapaporn
    Sudsai, Teeratad
    Septama, Abdi Wira
    Chukaew, Arnon
    Tewtrakul, Supinya
    ADVANCES IN PHARMACOLOGICAL SCIENCES, 2019, 2019
  • [47] Anti-cholinergic, cytotoxic and anti-HIV-1 activities of sesquiterpenes and a flavonoid glycoside from the aerial parts of Polygonum viscosum
    Datta, BK
    Datta, SK
    Khan, TH
    Kundu, JK
    Rashid, MA
    Nahar, L
    Sarker, SD
    PHARMACEUTICAL BIOLOGY, 2004, 42 (01) : 18 - 23
  • [48] In vitro anti-HIV-1 activities of kaempferol and kaempferol-7-Oglucoside isolated from Securigera securidaca
    Behbahani, M.
    Sayedipour, S.
    Pourazar, A.
    Shanehsazzadeh, M.
    RESEARCH IN PHARMACEUTICAL SCIENCES, 2014, 9 (06) : 463 - 469
  • [49] Cytotoxic, Antitopoisomerase IIα, and Anti-HIV-1 Activities of Triterpenoids Isolated from Leaves and Twigs of Gardenia carinata
    Kongkum, Naowarat
    Tuchinda, Patoomratana
    Pohmakotr, Manat
    Reutrakul, Vichai
    Piyachaturawat, Pawinee
    Jariyawat, Surawat
    Suksen, Kanoknetr
    Akkarawongsapat, Radeekorn
    Kasisit, Jitra
    Napaswad, Chanita
    JOURNAL OF NATURAL PRODUCTS, 2013, 76 (04): : 530 - 537
  • [50] Anti-HIV-1 activities in extracts from some medicinal plants as assessed in an in vitro biochemical HIV-1 reverse transcriptase assay
    Kanyara, JN
    Njagi, ENM
    PHYTOTHERAPY RESEARCH, 2005, 19 (04) : 287 - 290
12345