8-O-4′-Neolignans from the Stem Bark of Illicium difengpi and their ANTI-HIV-1 Activities

被引：0
|
作者：
Yuchun Yang
Ying Qin
Yanlin Meng
Congfang Xia
Xuemei Gao
Qiufen Hu
机构：
[1] Yunnan University of Nationalities,Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education
来源：
Chemistry of Natural Compounds | 2016年 / 52卷
关键词：
8-; -4′-neolignans; anti-HIV-1 activity;
D O I：
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学科分类号：
摘要：
Two new 8-O-4′-neolignans, difenneolignans A and B (1and2), together with six known neolignans (3–8), were isolated from the stem bark of Illicium difengpi. The structures of1–8were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds1and2were also tested for their anti-HIV-1 activities. The results revealed significant activities for compounds1and2with therapeutic index (TI) values of 95.5 and 114.4, respectively.
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页码：43 / 47
页数：4
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