Molecular and crystal structure of 4,6,6-trimethyl-2-oxo-5,6-dihydro-2H- pyran-3-carbonitrile and 4,6,6-trimethyl-2-oxo-1,2,5,6-tetrahydropyridine-3- carbonitrile

被引：0

作者：

Jansone D. ^{[1
]}

Belyakov S. ^{[1
]}

Fleisher M. ^{[1
]}

Leite L. ^{[1
]}

Lukevics E. ^{[1
]}

机构：

[1] Latvian Institute of Organic Synthesis

来源：

Chemistry of Heterocyclic Compounds | 2007年 / 43卷 / 11期

关键词：

4,6,6-trimethyl-2-oxo-1,2,5,6-tetrahydropyridine-3-carbonitrile; 4,6,6-trimethyl-2-oxo-5,6-dihydro-2H-pyran-3-carbonitrile; AM1; method; X-ray crystallographic analysis;

D O I：

10.1007/s10593-007-0212-9

中图分类号：

学科分类号：

摘要：

Single crystals of 4,6,6-trimethyl-2-oxo-5,6-dihydro-2H-pyran-3- carbonitrile and 4,6,6-trimethyl-2-oxo-1,2,5,6-tetrahydropyridine-3-carbonitrile were prepared and submitted to X-ray diffraction analysis. Both compounds have a molecular structure belonging to the C1 symmetry group. The heterocyclic rings are in a distorted envelope conformation. The crystals belong to the monoclinic system and each contain four molecules in the unit cell. In the crystal the pyridine derivative exists in the form of centrosymmetric dimers stabilized by intermolecular hydrogen bonds between the oxygen atoms of the carbonyl group and the hydrogen atom at the nitrogen atom of the ring. © 2007 Springer Science+Business Media, Inc.

引用

页码：1374 / 1378

页数：4

共 50 条

[41] 2-Amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
Wang, Xiaoli
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O832 - U105
[42] SYNTHESIS OF POLYNITROARYL DERIVATIVES OF 3-ARYL-1H,4H-DIHYDRO-4,6,6-TRIMETHYL-PYRIMIDINE-2-THIOLS AS POSSIBLE FUNGICIDES
SANGAL, SK
KUMAR, A
RASTOGI, P
PRAKASH, O
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1986, 63 (06) : 596 - 599
[43] Crystal structure of 2-amino-7-methyl-4-(3,4difluoro-phenyl)-5-oxo-4H, 5H-pyrano[4,3-b]pyran-3-carbonitrile, C16H10F2N2O3
Zheng, Dongjing
Yang, Yige
Li, Jing
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2016, 231 (04): : 1179 - 1180
[44] Crystal structure and Hirshfeld surface analysis of 5-acetyl-2-amino-4-(4-bromonhenyl)-6-oxo-1-phenyl-1,4,5,6-tetrahydropyridine-3-carbonitrile
Mamedov, Ibrahim G.
Khrustalev, Victor N.
Akkurt, Mehmet
Novikov, Anton P.
Asgarova, Ayten R.
Aliyeva, Khatira N.
Akobirshoeva, Anzurat A.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2022, 78 : 291 - +
[45] Crystal structure of 2-amino-4-(3,5-dibromo-4-hydroxyphenyl)-7-methyl-5-oxo-2H,5H-pyrano[4,3-b]pyran-3-carbonitrile, C16H10Br2N2O4
Li, Jing
Gou, Wei
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2018, 233 (04): : 597 - 598
[46] Crystal structure of 2-amino-4-(4-bromo-phenyl)-7-methyl-5-oxo-4H, 5H-pyrano[4,3-b]pyran-3-carbonitrile, C16H11BrN2O3
Yu, Xue-Jun
Zhao, Lin-Ping
Ma, Long-Ji
Gong, Hua-Fen
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2017, 232 (01): : 109 - 110
[47] 4-HYDROXY-2-QUINOLONES 172. SYNTHESIS AND STRUCTURE OF 4,3′-SPIRO[(6-ALLYL-2-AMINO-5-OXO-5,6-DIHYDRO-4H-PYRANO[3,2-c]QUINOLINE-3-CARBONITRILE)-2′-OXINDOLE]
Ukrainets, I. V.
Red'kin, R. G.
Sidorenko, L. V.
Turov, A. V.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2009, 45 (12) : 1478 - 1484
[48] A NOVEL SYNTHESIS OF 1,6-DIHYDRO-2-METHYL-6-OXO[3,4'BIPYRIDINE]-5-CARBONITRILE (MILRINONE)
SINGH, B
HETEROCYCLES, 1985, 23 (06) : 1479 - 1482
[49] Hepatoprotective activity of 6-(4-bromophenyl)-4-methylthio-2-oxo-2H-pyran-3-carbonitrile against hepatotoxicity induced by galactosamine and thioacetamide in rats
Rastogi, R
Saksena, S
Tripathi, SC
Hussaini, FA
Shoeb, A
Dhawan, BN
Ram, VJ
MEDICAL SCIENCE RESEARCH, 1998, 26 (11): : 729 - 731
[50] 4-(1,3-Benzodioxol-5-yl)-2-oxo-1,2,5,6-tetrahydrobenzo[h]quinoline-3-carbonitrile
Asiri, Abdullah M.
Faidallah, Hassan M.
Al-Youbi, Abdulrahman O.
Alamry, Khalid A.
Ng, Seik Weng
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2471 - U1517

← 1 2 3 4 5 →