Guillain–Barré syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c

被引：0
|
作者：
N. Scharn
T. Ganzenmueller
J. J. Wenzel
R. Dengler
A. Heim
F. Wegner
机构：
[1] Hannover Medical School,Department of Neurology
[2] Hannover Medical School,Institute of Virology
[3] University of Regensburg,Institute of Clinical Microbiology and Hygiene
来源：
Infection | 2014年 / 42卷
关键词：
Guillain–Barré syndrome; Hepatitis E virus; Subgenotype 3c;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In this report, we present a case of a 50-year-old immunocompetent man with Guillain–Barré syndrome (GBS) associated with an autochthonous hepatitis E virus (HEV) infection. The patient presented with tetraparesis and elevated liver enzymes. HEV infection was confirmed serologically and by polymerase chain reaction (PCR) from blood and stool. Phylogenetic analysis revealed a novel HEV genotype 3 isolate closely related to other subgenotype 3c isolates from pig livers purchased in Germany. This indicates an autochthonous, potentially food-related hepatitis E and is, to our knowledge, the first report about a neurological syndrome associated with an HEV subgenotype 3c infection.
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页码：171 / 173
页数：2
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