Metabolic Effects of Endoscopic Duodenal Mucosal Resurfacing: a Systematic Review and Meta-analysis

被引：0
|
作者：
Guilherme Henrique Peixoto de Oliveira
Diogo Turiani Hourneaux de Moura
Mateus Pereira Funari
Thomas R. McCarty
Igor Braga Ribeiro
Wanderley Marques Bernardo
Vitor Massaro Takamatsu Sagae
João Remi Freitas
Gabriel Mayo de Vieira Souza
Eduardo Guimarães Hourneaux de Moura
机构：
[1] University of São Paulo School of Medicine,Gastrointestinal Endoscopy Unit, Hospital das Clínicas
[2] Brigham and Women’s Hospital – Harvard Medical School,Division of Gastroenterology, Hepatology and Endoscopy
来源：
Obesity Surgery | 2021年 / 31卷
关键词：
Duodenal mucosal resurfacing; DMR; Diabetes; Hydrothermal ablation; Hepatic steatosis; Systematic review;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Duodenal mucosal resurfacing (DMR) is an innovative endoscopic bariatric and metabolic therapy (EBMT) emerging in recent years. It uses the duodenum to achieve better glycemic and weight control. This study aimed to evaluate in a critical and systematic way the metabolic effects of this procedure. Electronic searches were performed evaluating the DMR procedure based on predefined inclusion and exclusion criteria. Changes in measured outcomes were evaluated using random-effects models by computing weighted mean differences (MD) and corresponding 95% CIs between pre-and post-procedure metabolic characteristics. Four studies were selected for qualitative and quantitative analysis. DMR demonstrated beneficial glycemic and hepatic metabolic effects among patients with non-insulin dependent type 2 diabetes (T2D) at 3 and 6 months post-procedure.
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页码：1304 / 1312
页数：8
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