Investigations into the Technology of Vitamin B1: Optimization of the Synthesis of 4-Methyl-5-(β-acetoxyethyl)thiazole

被引：0
|
作者：
M. M. Litvak
机构：
[1] Belgorod State University,
来源：
Pharmaceutical Chemistry Journal | 2005年 / 39卷
关键词：
Acetate; Organic Chemistry; Thiamine; Thiazole; Direct Synthesis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The conversion of butyrolactone into 4-methyl-5-(β-acetoxyethyl)thiazole has been thoroughly studied and modified so as to use the latter compound for the direct synthesis of thiamine (vitamin B1) via thiamine acetate. The main modifications are related to the stage of decarboxylation of α-aceto-α-chlorobutyrolactone. The results can be of interest for specialists engaged in the technology of vitamin B1.
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页码：500 / 503
页数：3
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