25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end

被引：0
|
作者：
Markus H. Heim
机构：
[1] University of Basel,Markus H. Heim is at the Department of Biomedicine, Switzerland and at the Division of Gastroenterology and Hepatology
[2] 4031 Basel,undefined
[3] University Hospital Basel,undefined
[4] 4031 Basel,undefined
[5] Switzerland.,undefined
来源：
Nature Reviews Immunology | 2013年 / 13卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The mechanisms underlying the antiviral activity of type I interferons (IFNs) are still unclear, but IFNα has long been used in the treatment of chronic hepatitis C (CHC). While reviewing the history of IFNα-based CHC treatment, Markus H. Heim highlights the remaining questions and discusses the future challenges of IFN-based therapies.
引用
收藏
页码：535 / 542
页数：7
相关论文
共 50 条
  • [31] Neuropsychiatric status of 100 naive chronic hepatitis C patients ready to start interferon-based treatment.
    Belville-Robertson, TL
    Brown, KA
    Moonka, DK
    Mahr, G
    Clemensen, LR
    Lucas, MB
    Eshelman, AK
    HEPATOLOGY, 2001, 34 (04) : 217A - 217A
  • [32] Changes of shear-wave velocity by interferon-based therapy in chronic hepatitis C
    Osakabe, Keisuke
    Ichino, Naohiro
    Nishikawa, Toru
    Sugiyama, Hiroko
    Kato, Miho
    Shibata, Ai
    Asada, Wakana
    Kawabe, Naoto
    Hashimoto, Senju
    Murao, Michihito
    Nakano, Takuji
    Shimazaki, Hiroaki
    Kan, Toshiki
    Nakaoka, Kazunori
    Takagawa, Yuka
    Ohki, Masashi
    Kurashita, Takamitsu
    Takamura, Tomoki
    Yoshioka, Kentaro
    WORLD JOURNAL OF GASTROENTEROLOGY, 2015, 21 (35) : 10215 - 10223
  • [33] Changes of shear-wave velocity by interferon-based therapy in chronic hepatitis C
    Keisuke Osakabe
    Naohiro Ichino
    Toru Nishikawa
    Hiroko Sugiyama
    Miho Kato
    Ai Shibata
    Wakana Asada
    Naoto Kawabe
    Senju Hashimoto
    Michihito Murao
    Takuji Nakano
    Hiroaki Shimazaki
    Toshiki Kan
    Kazunori Nakaoka
    Yuka Takagawa
    Masashi Ohki
    Takamitsu Kurashita
    Tomoki Takamura
    Kentaro Yoshioka
    World Journal of Gastroenterology, 2015, (35) : 10215 - 10223
  • [34] Interferon-based therapy delays but metabolic comorbidity accelerates progression of chronic hepatitis C
    Martinez-Macias, Roberto F.
    Cordero-Perez, Paula
    Juarez-Rodriguez, Omar A.
    Chen-Lopez, Carlos Y.
    Martinez-Carrillo, Francisco M.
    Alarcon-Galvan, Gabriela
    Mercado-Hernandez, Roberto
    Munoz-Espinosa, Linda E.
    ANNALS OF HEPATOLOGY, 2015, 14 (01) : 36 - 45
  • [35] The prevalence of occult hepatitis B in chronic hepatitis C patients treated with interferon-based antiviral therapy
    Bal, Tayibe
    Onlen, Yusuf
    ARAB JOURNAL OF GASTROENTEROLOGY, 2018, 19 (01) : 33 - 36
  • [36] Direct costs of interferon-based and interferon-free direct-acting antiviral regimens for the treatment of chronic hepatitis C infection
    Gray, E.
    O'Leary, A.
    Kieran, J. A.
    Fogarty, E.
    Dowling, T.
    Norris, S.
    JOURNAL OF VIRAL HEPATITIS, 2016, 23 (09) : 677 - 686
  • [37] The risk of hepatocellular carcinoma and decompensation following hepatitis C treatment with interferon-based therapy
    Jamil, K. M.
    Cheng, W.
    Tarquinio, L.
    Adams, L.
    Mollison, L.
    Macquillan, G.
    Flexman, J.
    Deboer, B.
    Kontorinis, N.
    GUT, 2007, 56 : A126 - A126
  • [38] The treatment of hepatitis C with interferon-based therapy in patients on renal dialysis in Western Australia
    Wallace, M.
    Kontorinis, N.
    Tarquinio, L.
    Doyle, A.
    Thomas, M.
    Nazareth, S.
    Mcinerney, M.
    Flexman, J.
    Cheng, W.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2010, 25 : A128 - A129
  • [39] Risk of infections during interferon-based treatment in patients with chronic hepatitis C virus infection and advanced hepatic fibrosis
    Maan, Raoel
    van der Meer, Adriaan J.
    Hansen, Bettina E.
    Feld, Jordan J.
    Wedemeyer, Heiner
    Dufour, Jean-Francois
    Lammert, Frank
    Manns, Michael P.
    Zeuzem, Stefan
    Janssen, Harry L. A.
    de Knegt, Robert J.
    Veldt, Bart J.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2015, 30 (06) : 1057 - 1064
  • [40] INCIDENCE AND RISK FACTORS FOR INFECTIONS DURING INTERFERON-BASED TREATMENT OF CHRONIC HEPATITIS C PATIENTS WITH ADVANCED HEPATIC FIBROSIS
    Maan, R.
    van der Meer, A. J.
    Hansen, B. E.
    Feld, J. J.
    Wedemeyer, H.
    Dufour, J. -F.
    Zangneh, H. F.
    Lammert, F.
    Manns, M. P.
    Zeuzem, S.
    Janssen, H. L. A.
    de Knegt, R. J.
    Veldt, B. J.
    JOURNAL OF HEPATOLOGY, 2014, 60 (01) : S477 - S477
12345