Common genetic variants, acting additively, are a major source of risk for autism

被引:0
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作者
Lambertus Klei
Stephan J Sanders
Michael T Murtha
Vanessa Hus
Jennifer K Lowe
A Jeremy Willsey
Daniel Moreno-De-Luca
Timothy W Yu
Eric Fombonne
Daniel Geschwind
Dorothy E Grice
David H Ledbetter
Catherine Lord
Shrikant M Mane
Christa Lese Martin
Donna M Martin
Eric M Morrow
Christopher A Walsh
Nadine M Melhem
Pauline Chaste
James S Sutcliffe
Matthew W State
Edwin H Cook
Kathryn Roeder
Bernie Devlin
机构
[1] University of Pittsburgh School of Medicine,Department of Psychiatry
[2] Yale University School of Medicine,Program on Neurogenetics
[3] Yale University School of Medicine,Child Study Center
[4] Yale University School of Medicine,Department of Psychiatry
[5] Yale University School of Medicine,Department of Genetics
[6] University of Michigan,Department of Psychology
[7] Semel Institute,Neurogenetics Program, Department of Neurology and Center for Autism Research and Treatment
[8] David Geffen School of Medicine,Department of Human Genetics
[9] University of California Los Angeles,Division of Genetics
[10] Emory University School of Medicine,Department of Psychiatry
[11] Children's Hospital Boston,Department of Psychiatry
[12] Harvard Medical School,Center for Autism and the Developing Brain
[13] McGill University,Departments of Pediatrics and Human Genetics
[14] Montreal Children's Hospital,Department of Molecular Biology
[15] Mount Sinai School of Medicine,Department of Psychiatry and Human Behavior
[16] Geisinger Health System,Howard Hughes Medical Institute and Division of Genetics
[17] Weill Cornell Medical College,Department of Molecular Physiology & Biophysics
[18] Yale Center for Genome Analysis,Institute for Juvenile Research
[19] The University of Michigan Medical Center,Department of Statistics
[20] Cell Biology and Biochemistry,undefined
[21] Brown University,undefined
[22] Brown University,undefined
[23] Children's Hospital Boston,undefined
[24] and Neurology and Pediatrics,undefined
[25] Harvard Medical School Center for Life Sciences,undefined
[26] Center for Molecular Neuroscience,undefined
[27] Vanderbilt University,undefined
[28] Department of Psychiatry,undefined
[29] University of Illinois at Chicago,undefined
[30] Carnegie Mellon University,undefined
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关键词
Narrow-sense heritability; Multiplex; Simplex; Quantitative genetics;
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