Vaterite deposition on biodegradable polymer foam scaffolds for inducing bone-like hydroxycarbonate apatite coatings

被引：0
|
作者：
H. Maeda
V. Maquet
T. Kasuga
Q. Z. Chen
J. A. Roether
A. R. Boccaccini
机构：
[1] Graduate School of Engineering,Department of Materials Science and Engineering
[2] Nagoya Institute of Technology,Centre for Education and Research on Macromolecules (CERM), Interfaculty Centre for Biomaterials
[3] University of Lige,Department of Materials
[4] Imperial College London,undefined
来源：
Journal of Materials Science: Materials in Medicine | 2007年 / 18卷
关键词：
Foam; Simulated Body Fluid; Bone Tissue Engineering; Vaterite; Simulated Body Fluid Solution;
D O I：
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中图分类号：
学科分类号：
摘要：
Hydroxycarbonate apatite (HCA) coatings on the surface of bioresorbable materials for bone tissue engineering scaffolds were produced using macroporous poly(DL-lactide) (PDLLA) foams impregnated by calcium carbonate in vaterite crystalline form. Stable and homogeneous vaterite deposition on PDLLA foams was achieved using a slurry dipping technique. In vitro studies in simulated body fluid (SBF) were performed to induce formation of (HCA) on the surface of vaterite/PDLLA composite foams. HCA was detected after immersion of foams in SBF for 7 days. Hence, depositing vaterite on materials followed by immersion in SBF is confirmed to induce HCA coatings on the surface of the material. The HCA coated, bioactive and resorbable PDLLA foams are intended for use as bone tissue engineering scaffolds.
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页码：2269 / 2273
页数：4
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