Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth

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作者
Yizheng Zhang
Chuchu Zhang
Jiehan Li
Meimei Jiang
Shuning Guo
Ge Yang
Lingling Zhang
Feng Wang
Shiqi Yi
Jiangang Wang
Yang Fu
Yingjie Zhang
机构
[1] The Third Xiangya Hospital,Department of Health Management
[2] Central South University,Department of Gastrointestinal Surgery
[3] The First Affiliated Hospital of Zhengzhou University,School of Biomedical Sciences
[4] Hunan University,Department of Ophthalmology
[5] The First Affiliated Hospital of Zhengzhou University,Department of Laboratory Medicine
[6] The Third Xiangya Hospital,Department of Gastroenterology
[7] Central South University,Center for Reproductive Medicine
[8] The Tenth People’s Hospital of Shanghai,College of Biology
[9] Tongji University,Department of Pathology and Neuropathology
[10] The First Affiliated Hospital of Zhengzhou University,undefined
[11] Hunan University,undefined
[12] University Hospital Tuebingen,undefined
关键词
AKT; p53; Parthanatos; Cell death; SIRT6; Colorectal cancer;
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