PS - 46. SIRT3 overexpression in rat skeletal muscle does not alleviate high-fat diet-induced insulin resistance

被引:0
|
作者
Joris Hoeks
Lauren Wright
Johanna A Jörgensen
Brenna Osborne
Magdalene Montgomery
Greg Cooney
Patrick Schrauwen
Nigel Turner
机构
[1] Maastricht University Medical Centre,dept. of Human Biology
[2] Garvan Institute of Medical Research,undefined
关键词
SIRT3 Protein; SIRT3 Overexpression; SIRT3 Level; Human Insulin Resistance; SIRT3 Protein Level;
D O I
10.1007/s12467-012-0080-5
中图分类号
学科分类号
摘要
Intramuscular fat accumulation, skeletal muscle mitochondrial dysfunction and oxidative stress have all been implicated in the development of human insulin resistance and type 2 diabetes mellitus (T2DM).
引用
收藏
页码:130 / 130
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