Synthesis of 1,2,4,5-tetrazines, symmetrically and unsymmetrically 3,6-disubstituted by N-nucleophiles

被引：0
|
作者：
G. L. Rusinov
N. I. Latosh
I. I. Ganebnykh
R. I. Ishmetova
N. K. Ignatenko
O. N. Chupakhin
机构：
[1] Russian Academy of Sciences,Postovskii Institute of Organic Synthesis, Ural Division
来源：
Russian Journal of Organic Chemistry | 2006年 / 42卷
关键词：
Benzylamine; Benzotriazole; Tetrazine; Hydrazino; Primary Aliphatic Amine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
6-R-3-(3,5-Dimethylpyrazol-1-yl)-1,2,4,5-tetrazines with aliphatic, cycloaliphatic, and aromatic amines, and also with NH-heterocycles undergo a nucleophilic substitution of the dimethylpyrazole moiety yielding symmetrically and unsymmetrically substituted 1,2,4,5-tetrazines. In the 3,6-diimidazolyl-and 3,6-dibenzotriazolyl derivatives reactions of nucleophilic substitution of the heterocyclic moiety also occur. In some cases an ipsosubstitution of amino, hydrazino, and azido groups is observed.
引用
收藏
页码：757 / 765
页数：8
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