Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer’s disease model

被引:0
|
作者
Fernando Goñi
Mitchell Martá-Ariza
Krystal Herline
Daniel Peyser
Allal Boutajangout
Pankaj Mehta
Eleanor Drummond
Frances Prelli
Thomas Wisniewski
机构
[1] New York University School of Medicine,Center for Cognitive Neurology and Department of Neurology
[2] New York University School of Medicine,Department of Pathology
[3] New York University School of Medicine,Department of Psychiatry
[4] New York State Institute for Basic Research in Developmental Disabilities,Department of Immunology
关键词
Immunomodulation; Oligomers; Amyloid-β; Tau; Prion;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Nanotechnology for tau pathology in Alzheimer's disease
    Ma, Rongrong
    Mu, Qianwen
    Xi, Yue
    Liu, Gang
    Liu, Chao
    [J]. MATERIALS TODAY BIO, 2024, 27
  • [22] The neurofibrillary pathology of tau in Alzheimer'S disease
    Garcia-Sierra, F.
    Ibarra Bracamontes, V. J.
    Magana Aguirre, J. J.
    Kristofikova, Z.
    Ripova, D.
    [J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 2017, 381 : 327 - 327
  • [23] Induction and spreading of tau pathology in a mouse model of Alzheimer's disease
    Clavaguera, Florence
    Goedert, Michel
    ToInay, Markus
    [J]. M S-MEDECINE SCIENCES, 2010, 26 (02): : 121 - 124
  • [24] Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice
    Liu, Wencheng
    Zhao, Lingzhi
    Blackman, Brittany
    Parmar, Mayur
    Wong, Man Ying
    Woo, Thomas
    Yu, Fangmin
    Sondhi, Dolan
    Kaminsky, Stephen M.
    Crystal, Ronald G.
    Paul, Steven M.
    [J]. JOURNAL OF NEUROSCIENCE, 2016, 36 (49): : 12425 - 12435
  • [25] Molecular mechanism of novel anti-phospho-tau serine 396/404 scFv antibody on reversal of tau pathology in Alzheimer's disease
    Ng, Pei Ying
    Chye, Soi Moi
    [J]. JOURNAL OF NEUROCHEMISTRY, 2023, 166 : 129 - 129
  • [26] Inhibition of EV Biogenesis Reduces Tau Propagation in a Seeded Tau Model of Alzheimer's Disease
    Tallon, Carolyn
    Bell, Benjamin J.
    Malvankar, Medhinee M.
    Coleman, Kaleem
    Joe, Tawnjerae R.
    Sharma, Anjali
    Eren, Erden
    Rangaramanujam, Kannan
    Kapogiannis, Dimitrios
    Slusher, Barbara S.
    [J]. NEUROTHERAPEUTICS, 2022, 19 (04) : 1424 - 1424
  • [27] Immunotherapy for Alzheimer's disease: from anti-β-amyloid to tau-based immunization strategies
    Panza, Francesco
    Frisardi, Vincenza
    Solfrizzi, Vincenzo
    Imbimbo, Bruno P.
    Logroscino, Giancarlo
    Santamato, Andrea
    Greco, Antonio
    Seripa, Davide
    Pilotto, Alberto
    [J]. IMMUNOTHERAPY, 2012, 4 (02) : 213 - 238
  • [28] Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer's disease
    Sun, Xiao-ying
    Li, Ling-jie
    Dong, Quan-Xiu
    Zhu, Jie
    Huang, Ya-ru
    Hou, Sheng-jie
    Yu, Xiao-lin
    Liu, Rui-tian
    [J]. JOURNAL OF NEUROINFLAMMATION, 2021, 18 (01)
  • [29] Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease
    Xiao-ying Sun
    Ling-jie Li
    Quan-Xiu Dong
    Jie Zhu
    Ya-ru Huang
    Sheng-jie Hou
    Xiao-lin Yu
    Rui-tian Liu
    [J]. Journal of Neuroinflammation, 18
  • [30] Cerebrovascular disease promotes tau pathology in Alzheimer's disease
    Laing, Krystal K.
    Simoes, Sabrina
    Baena-Caldas, Gloria P.
    Lao, Patrick J.
    Kothiya, Milankumar
    Igwe, Kay C.
    Chesebro, Anthony G.
    Houck, Alexander L.
    Pedraza, Lina
    Hernandez, A. Ivan
    Li, Jie
    Zimmerman, Molly E.
    Luchsinger, Jose A.
    Barone, Frank C.
    Moreno, Herman
    Brickman, Adam M.
    [J]. BRAIN COMMUNICATIONS, 2020, 2 (02)