Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

被引:0
|
作者
Jun Zhu
Bin Zhang
Erin N Smith
Becky Drees
Rachel B Brem
Leonid Kruglyak
Roger E Bumgarner
Eric E Schadt
机构
[1] Rosetta Inpharmatics,Lewis
[2] LLC,Sigler Institute for Integrative Genomics and Department of Ecology and Evolutionary Biology
[3] Princeton University,Department of Molecular and Cellular Biology
[4] Carl Icahn Laboratory,Department of Microbiology
[5] Box 357275,Department of Molecular and Cell Biology
[6] University of Washington,undefined
[7] Box 358070,undefined
[8] University of Washington,undefined
[9] 304A Stanley Hall #3220,undefined
[10] University of California,undefined
[11] Berkeley,undefined
来源
Nature Genetics | 2008年 / 40卷
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学科分类号
摘要
Eric Schadt and colleagues report the construction of yeast regulatory networks from multiple sources of large-scale functional genomic data, and show that a network constructed from the integration of genotypic, transcription factor binding site, and protein–protein interaction data is the most predictive.
引用
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页码:854 / 861
页数:7
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