Protein-protein interaction networks in the spinocerebellar ataxias

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作者
David C Rubinsztein
机构
[1] Wellcome/MRC Building,Department of Medical Genetics, Cambridge Institute for Medical Research
[2] Addenbrooke's Hospital,undefined
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关键词
Spinocerebellar Ataxia; Spinocerebellar Ataxia Type; Disease Protein; Yeast Nucleus; Autosomal Dominant Spinocerebellar Ataxia;
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摘要
A large yeast two-hybrid study investigating whether the proteins mutated in different forms of spinocerebellar ataxia have interacting protein partners in common suggests that some forms do share common pathways, and will provide a valuable resource for future work on these diseases.
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