Next generation oncology drug development: opportunities and challenges

被引：0
|
作者：
Martin E. Gutierrez
Shivaani Kummar
Giuseppe Giaccone
机构：
[1] National Cancer Institute,
来源：
Nature Reviews Clinical Oncology | 2009年 / 6卷
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D O I：
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学科分类号：
摘要：
The development of novel molecularly targeted agents requires a re-evaluation of the current drug development paradigm. Gutierrez et al. discuss the opportunities and challenges facing drug development in the oncology field, such as optimum clinical trial design, patient selection, optimal biologic dose versus maximum tolerated dose, and definition of response criteria and suitable endpoints for clinical trials.
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页码：259 / 265
页数：6
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