Is bigger better?

被引：0
|
作者：
Robert C. Malenka
Roger A. Nicoll
机构：
[1] University of California,the Departments of Psychiatry and Physiology, and Roger A. Nicoll is in the Departments of Cellular and Molecular Physiology and Physiology
来源：
Nature | 1998年 / 396卷
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摘要：
There is plenty of indirect evidence that the postsynaptic density (PSD)-95 protein is involved in the clustering and, perhaps, targeting of postsynaptic proteins. Direct evidence was lacking, but PSD-95 knockout mice have now arrived, and their properties support a clustering function. However, knocking out PSD-95 also disrupts synaptic plasticity, and this could mean that PSD-95 acts as a kind of scaffold protein.
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页码：414 / 415
页数：1
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