Genome-wide association study indicates two novel resistance loci for severe malaria

被引:0
|
作者
Christian Timmann
Thorsten Thye
Maren Vens
Jennifer Evans
Jürgen May
Christa Ehmen
Jürgen Sievertsen
Birgit Muntau
Gerd Ruge
Wibke Loag
Daniel Ansong
Sampson Antwi
Emanuel Asafo-Adjei
Samuel Blay Nguah
Kingsley Osei Kwakye
Alex Osei Yaw Akoto
Justice Sylverken
Michael Brendel
Kathrin Schuldt
Christina Loley
Andre Franke
Christian G. Meyer
Tsiri Agbenyega
Andreas Ziegler
Rolf D. Horstmann
机构
[1] Bernhard Nocht Institute for Tropical Medicine,Department of Molecular Medicine
[2] 20359 Hamburg,undefined
[3] Germany,undefined
[4] Institute of Medical Biometry and Statistics,undefined
[5] University at Lübeck,undefined
[6] 23562 Lübeck,undefined
[7] Germany,undefined
[8] Kumasi Centre for Collaborative Research in Tropical Medicine,undefined
[9] Infectious Disease Epidemiology Group,undefined
[10] Bernhard Nocht Institute for Tropical Medicine,undefined
[11] 20359 Hamburg,undefined
[12] Germany,undefined
[13] School of Medical Sciences,undefined
[14] Kwame Nkrumah University of Science and Technology,undefined
[15] Institute of Clinical Molecular Biology,undefined
[16] Christian Albrechts University of Kiel,undefined
[17] 24105 Kiel,undefined
[18] Germany,undefined
来源
Nature | 2012年 / 489卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
A genome-wide association study in Ghana, West Africa, to identify genetic variants associated with malaria pathogenesis reveals two previously unknown loci on chromosomes 1 and 16.
引用
收藏
页码:443 / 446
页数:3
相关论文
共 50 条
  • [31] Genome-wide association study identifies novel breast cancer susceptibility loci
    Douglas F. Easton
    Karen A. Pooley
    Alison M. Dunning
    Paul D. P. Pharoah
    Deborah Thompson
    Dennis G. Ballinger
    Jeffery P. Struewing
    Jonathan Morrison
    Helen Field
    Robert Luben
    Nicholas Wareham
    Shahana Ahmed
    Catherine S. Healey
    Richard Bowman
    Kerstin B. Meyer
    Christopher A. Haiman
    Laurence K. Kolonel
    Brian E. Henderson
    Loic Le Marchand
    Paul Brennan
    Suleeporn Sangrajrang
    Valerie Gaborieau
    Fabrice Odefrey
    Chen-Yang Shen
    Pei-Ei Wu
    Hui-Chun Wang
    Diana Eccles
    D. Gareth Evans
    Julian Peto
    Olivia Fletcher
    Nichola Johnson
    Sheila Seal
    Michael R. Stratton
    Nazneen Rahman
    Georgia Chenevix-Trench
    Stig E. Bojesen
    Børge G. Nordestgaard
    Christen K. Axelsson
    Montserrat Garcia-Closas
    Louise Brinton
    Stephen Chanock
    Jolanta Lissowska
    Beata Peplonska
    Heli Nevanlinna
    Rainer Fagerholm
    Hannaleena Eerola
    Daehee Kang
    Keun-Young Yoo
    Dong-Young Noh
    Sei-Hyun Ahn
    Nature, 2007, 447 : 1087 - 1093
  • [32] Genome-Wide Association Study for Waldenstrom Macroglobulinemia Identifies Novel Susceptibility Loci
    McMaster, Mary L.
    Berndt, Sonja I.
    Zhang, Jianqing
    Slager, Susan L.
    Li, Shengchao
    Brown, Elizabeth E.
    Ekstrom-Smedby, Karin
    Kleinstern, Geffen
    Zhu, Bin
    Chung, Charles
    Burdette, Laurie
    Park, Ju-Hyun
    Birmann, Brenda M.
    Link, Brian K.
    McKay, James
    Monnereau, Alain
    Morton, Lindsay M.
    Nieters, Alexandra
    Smith, Alex
    Vermeulen, Roel
    Hjalgrim, Henrik
    Vajdic, Claire
    Teras, Lauren
    Hicks, Belynda
    Chatterjee, Nilanjan
    Rothman, Nathaniel
    Offit, Kenneth
    Cerhan, James R.
    Vijai, Joseph
    Goldin, Lynn R.
    Skibola, Christine F.
    Caporaso, Neil E.
    BLOOD, 2017, 130
  • [33] Extended genome-wide association study in the United Kingdom revealing novel susceptibility loci for severe Acne vulgaris
    Navarini, A. A.
    EXPERIMENTAL DERMATOLOGY, 2016, 25 : 50 - 50
  • [34] Genome-wide Association Study Meta-analysis Identifies Novel Susceptibility Loci for Severe Diabetic Retinopathy
    Tikhomirov, Anna
    Grassi, Michael A.
    Ramalingam, Sudha
    Below, Jennifer E.
    Cox, Nancy J.
    Nicolae, Dan L.
    GENETIC EPIDEMIOLOGY, 2010, 34 (08) : 954 - 955
  • [35] Genome-wide association study to identify soybean stem pushing resistance and lodging resistance loci
    Kato, Shin
    Samanfar, Bahram
    Morrison, Malcolm J.
    Bekele, Wubishet A.
    Torkamaneh, Davoud
    Rajcan, Istvan
    O'Donoughue, Louise
    Belzile, Francois
    Cober, Elroy R.
    CANADIAN JOURNAL OF PLANT SCIENCE, 2021, 101 (05) : 663 - 670
  • [36] Genome-wide association identified novel loci contributing to ROP
    Owen, Leah
    Li, Xiaohui
    Taylor, Kent
    Ostmo, Susan
    Chen, Y.
    Coyner, Aaron
    Sonmez, Kemal
    Hartnett, Mary
    Chan, Robison
    DeAngelis, Margaret
    Chiang, Michael
    Campbell, J.
    Rotter, Jerome
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023, 64 (08)
  • [37] Genome-Wide Association Studies for Predisposition to Severe Diabetic Retinopathy Reveal Novel Susceptibility Loci
    Grassi, M. A.
    Rannalingam, S.
    Klein, R.
    Klein, B. E.
    Lee, K. E.
    Lee, Y.
    Li, J.
    Lussier, Y. A.
    Cox, N. J.
    Nicolae, D. L.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2010, 51 (13)
  • [38] Detecting novel loci underlying rice blast resistance by integrating a genome-wide association study and RNA sequencing
    Qing Lu
    Caihong Wang
    Xiaojun Niu
    Mengchen Zhang
    Qun Xu
    Yue Feng
    Yaolong Yang
    Shan Wang
    Xiaoping Yuan
    Hanyong Yu
    Yiping Wang
    Xinghua Wei
    Molecular Breeding, 2019, 39
  • [39] Genome-Wide Association Study Reveals Novel Loci for SC7 Resistance in a Soybean Mutant Panel
    Che, Zhijun
    Liu, Hailun
    Yi, Fanglei
    Cheng, Hao
    Yang, Yuming
    Wang, Li
    Du, Jingyi
    Zhang, Peipei
    Wang, Jiao
    Yu, Deyue
    FRONTIERS IN PLANT SCIENCE, 2017, 8
  • [40] Detecting novel loci underlying rice blast resistance by integrating a genome-wide association study and RNA sequencing
    Lu, Qing
    Wang, Caihong
    Niu, Xiaojun
    Zhang, Mengchen
    Xu, Qun
    Feng, Yue
    Yang, Yaolong
    Wang, Shan
    Yuan, Xiaoping
    Yu, Hanyong
    Wang, Yiping
    Wei, Xinghua
    MOLECULAR BREEDING, 2019, 39 (06)