Modeling cytokine release syndrome

被引:0
|
作者
Cliona Rooney
Tim Sauer
机构
[1] Baylor College of Medicine,Center for Cell and Gene Therapy, Department of Pediatrics
来源
Nature Medicine | 2018年 / 24卷
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摘要
Complete leukemic responses to chimeric antigen receptor–modified T cells are invariably accompanied by severe toxicity. Recently developed animal models allow mechanistic dissection and prevention of toxicity without loss of therapeutic benefit.
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页码:705 / 706
页数:1
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