Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells

被引:0
|
作者
Nan Huang
Yaxun Wei
Yi Cheng
Xiaolong Wang
Qi Wang
Dong Chen
Wenjing Li
机构
[1] Huazhong University of Science and Technology,Department of Allergy, Tongji Hospital, Tongji Medical College
[2] ABLife Inc.,Center for Genome Analysis
[3] Huazhong University of Science and Technology,Oncology Department, Tongji Hospital, Tongji Medical College
[4] Wuhan Ruixing Biotechnology Co. Ltd.,Science Department
来源
Genes & Genomics | 2022年 / 44卷
关键词
TFR1; RNA-seq; Gene expression; Alternative splicing; Cell physiology;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:637 / 650
页数:13
相关论文
共 50 条
  • [31] The hereditary hemochromatosis protein, HFE, lowers intracellular iron levels independently of transferrin receptor 1 in TRVb cells
    Carlson, H
    Zhang, AS
    Fleming, WH
    Enns, CA
    BLOOD, 2005, 105 (06) : 2564 - 2570
  • [32] Expression of cancer stem markers could be influenced by silencing of p16 gene in HeLa cervical carcinoma cells
    Wu, H.
    Zhang, J.
    Shi, H.
    EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2016, 37 (02) : 221 - 225
  • [33] RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing
    Qiuxia Yan
    Peng Zeng
    Xiuqin Zhou
    Xiaoying Zhao
    Runqiang Chen
    Jing Qiao
    Ling Feng
    Zhenjie Zhu
    Guozhi Zhang
    Cairong Chen
    Oncogene, 2021, 40 : 2635 - 2650
  • [34] RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing
    Yan, Qiuxia
    Zeng, Peng
    Zhou, Xiuqin
    Zhao, Xiaoying
    Chen, Runqiang
    Qiao, Jing
    Feng, Ling
    Zhu, Zhenjie
    Zhang, Guozhi
    Chen, Cairong
    ONCOGENE, 2021, 40 (15) : 2635 - 2650
  • [35] Transferrin receptor regulates malignancies and the stemness of hepatocellular carcinoma-derived cancer stem-like cells by affecting iron accumulation
    Xiao, Chong
    Fu, Xi
    Wang, Yuting
    Liu, Hong
    Jiang, Yifang
    Zhao, Ziyi
    You, Fengming
    PLOS ONE, 2020, 15 (12):
  • [36] Decreased Expression of Karyopherin-α 1 is Related to the Malignant Degree of Cervical Cancer and is Critical for the Proliferation of Hela Cells
    Jiang, Lucen
    Li, Dan
    Wang, Chao
    Liao, Jia
    Liu, Jianghuan
    Wei, Qingzhu
    Wang, Yiyang
    PATHOLOGY & ONCOLOGY RESEARCH, 2022, 28
  • [37] Adenovirus-mediated expression of UHRF1 reduces the radiosensitivity of cervical cancer HeLa cells to γ-irradiation
    Xin-li Li
    Qing-hui Meng
    Sai-jun Fan
    Acta Pharmacologica Sinica, 2009, 30 : 458 - 466
  • [38] Adenovirus-mediated expression of UHRF1 reduces the radiosensitivity of cervical cancer HeLa cells to γ-irradiation
    Li, Xin-li
    Meng, Qing-hui
    Fan, Sai-jun
    ACTA PHARMACOLOGICA SINICA, 2009, 30 (04) : 458 - 466
  • [39] Iron regulatory protein 1 is not required for the modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line
    Schalinske, KL
    Blemings, KP
    Steffen, DW
    Chen, OS
    Eisenstein, RS
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (20) : 10681 - 10686
  • [40] Expression of transferrin receptor/TFRC protein in bladder cancer cell T24 and its role in inducing iron death in bladder cancer
    Qin, Junkai
    Li, Zhidan
    Su, Lize
    Wen, Xilin
    Tang, Xingzhi
    Huang, Minyu
    Wu, Jun
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 274