Shortened ex vivo manufacturing time of EGFRvIII-specific chimeric antigen receptor (CAR) T cells reduces immune exhaustion and enhances antiglioma therapeutic function

被引:0
|
作者
Hillary G. Caruso
Ryuma Tanaka
Jiyong Liang
Xiaoyang Ling
Aria Sabbagh
Verlene K. Henry
Tiara L. Collier
Amy B. Heimberger
机构
[1] The University of Texas MD Anderson Cancer Center,Division of Pediatrics
[2] The University of Texas MD Anderson Cancer Center,Department of Neurosurgery
来源
Journal of Neuro-Oncology | 2019年 / 145卷
关键词
Chimeric antigen receptor T cell; Exhaustion markers; PD-1; PD-L1; LAG-3; TIM-3;
D O I
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中图分类号
学科分类号
摘要
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页码:429 / 439
页数:10
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