Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

被引：0
|
作者：
Michael K. Kiessling
Sven Schuierer
Silke Stertz
Martin Beibel
Sebastian Bergling
Judith Knehr
Walter Carbone
Cheryl de Vallière
Joelle Tchinda
Tewis Bouwmeester
Klaus Seuwen
Gerhard Rogler
Guglielmo Roma
机构：
[1] University Hospital Zürich,Department of Gastroenterology and Hepatology
[2] Novartis Institutes for Biomedical Research,Institute of Medical Virology
[3] Novartis Pharma AG,Department of Oncology
[4] University of Zürich,undefined
[5] Children University Hospital Zürich,undefined
来源：
BMC Genomics | / 17卷
关键词：
Whole genome CRISPR screen; Dropout; Negative selection; Driver mutations; EGFR; NRAS; Kinase;
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