Double overexpression of miR-19a and miR-20a in induced pluripotent stem cell-derived mesenchymal stem cells effectively preserves the left ventricular function in dilated cardiomyopathic rat

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作者
Jiunn-Jye Sheu
Han-Tan Chai
Pei-Hsun Sung
John Y. Chiang
Tien-Hung Huang
Pei-Lin Shao
Shun-Cheng Wu
Hon-Kan Yip
机构
[1] Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine,Division of Thoracic and Cardiovascular Surgery, Department of Surgery
[2] Kaohsiung Chang Gung Memorial Hospital and Chang Gung University,Division of Cardiology, Department of Internal Medicine
[3] College of Medicine,Center for Shockwave Medicine and Tissue Engineering
[4] Kaohsiung Chang Gung Memorial Hospital,Institute for Translational Research in Biomedicine
[5] Kaohsiung Chang Gung Memorial Hospital,Department of Computer Science and Engineering
[6] National Sun Yat-Sen University,Department of Healthcare Administration and Medical Informatics
[7] Kaohsiung Medical University,Department of Nursing
[8] Asia University,Regenerative Medicine and Cell Therapy Research Center
[9] Kaohsiung Medical University,Orthopaedic Research Center
[10] Kaohsiung Medical University,Post
[11] Asia University,Baccalaureate Program in Nursing
[12] China Medical University,Department of Medical Research, China Medical University Hospital
[13] Xiamen Chang Gung Hospital,Division of Cardiology, Department of Internal Medicine
关键词
Dilated cardiomyopathy; Double overexpression of microRNAs; Oxidative stress; Inflammation; Mitochondrial damage;
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