Evaluation of the expression of early activation marker CD69 by CD8+ lymphocytes in HIV-infected patients

被引：0
|
作者：
I. V. Isakov
L. M. Kurtasova
机构：
[1] Krasnoyarsk State Medical Academy,
[2] Regional Center on Prophylaxis and Combating of AIDS and Infection Diseases,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2007年 / 144卷
关键词：
HIV infection; immunophenotype; CD69 antigen;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We studied the expression of CD69 antigen on CD8+ lymphocytes in response to nonspecific activator phytohemagglutinin in 202 patients with HIV infection. It was found that the number of CD8+CD69+ lymphocytes in HIV-infected patients increased; this parameter negatively correlated with relative and absolute content of CD4+ cells and positively correlated with IgG concentration.
引用
收藏
页码：810 / 812
页数：2
相关论文
共 50 条
  • [31] CONTRASTING QUANTITATIVE ALTERATIONS IN CD4+ AND CD8+ LYMPHOCYTES IN HIV-INFECTED AFRICAN AMERICANS COMPARED WITH THE CAUCASIAN POPULATION
    CRUSE, JM
    BRACKIN, MN
    LEWIS, RE
    BRACKIN, BT
    PATHOLOGY AND IMMUNOPATHOLOGY RESEARCH, 1989, 8 (5-6): : 300 - 313
  • [32] Expression of the activation antigen CD69 predicts functionality of in vitro expanded peripheral blood mononuclear cells (PBMC) from healthy donors and HIV-infected patients
    Nielsen, SD
    Afzelius, P
    Ersboll, AK
    Nielsen, JO
    Hansen, JES
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1998, 114 (01): : 66 - 72
  • [33] EXPRESSION OF EARLY ACTIVATION ANTIGEN (CD69) DURING HUMAN THYMIC DEVELOPMENT
    JUNG, LKL
    HAYNES, BF
    NAKAMURA, S
    PAHWA, S
    FU, SM
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1990, 81 (03): : 466 - 474
  • [34] Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals
    Paiardini, M
    Cervasi, B
    Albrecht, H
    Muthukumar, A
    Dunham, R
    Gordon, S
    Radziewicz, H
    Piedimonte, G
    Magnani, M
    Montroni, M
    Kaech, SM
    Weintrob, A
    Altman, JD
    Sodora, DL
    Feinberg, MB
    Silvestri, G
    JOURNAL OF IMMUNOLOGY, 2005, 174 (05): : 2900 - 2909
  • [35] Evaluation of CD25 and CD69 activation markers expression on peripheral blood cells subpopulations in endometriosis patients
    Abramiuk, M.
    Dymanowska-Dyjak, I.
    Grywalska, E.
    Polak, G.
    HUMAN REPRODUCTION, 2023, 38
  • [36] Decreased frequency of CD73+ CD8+ T cells of HIV-infected patients correlates with immune activation and T cell exhaustion
    Toth, Ilona
    Le, Anh Q.
    Hartjen, Philip
    Thomssen, Adriana
    Matzat, Verena
    Lehmann, Clara
    Scheurich, Christoph
    Beisel, Claudia
    Busch, Philipp
    Degen, Olaf
    Lohse, Ansgar W.
    Eiermann, Thomas
    Faetkenheuer, Gerd
    Meyer-Olson, Dirk
    Bockhorn, Maximilian
    Hauber, Joachim
    van Lunzen, Jan
    zur Wiesch, Julian Schulze
    JOURNAL OF LEUKOCYTE BIOLOGY, 2013, 94 (04) : 551 - 561
  • [37] Decrease in surface expression of early activation marker CD 69 on CD 4+ lymphocytes in response to fasting in rheumatoid arthritis patients.
    Fraser, D
    Thoen, I
    Forre, O
    Kjeldsen-Kragh, J
    FASEB JOURNAL, 1998, 12 (05): : A871 - A871
  • [38] Expression of CD69 after in vitro stimulation: A rapid method for quantitating impaired lymphocyte responses in HIV-infected individuals
    Krowka, JF
    Cuevas, B
    Maron, DC
    Steimer, KS
    Ascher, MS
    Sheppard, HW
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1996, 11 (01): : 95 - 104
  • [39] CD8+ lymphocytes in pregnancy and HIV infection:: Characterization of CD8+ subpopulations and CD8+ noncytotoxic antiviral activity
    Rich, KC
    Siegel, JN
    Jennings, C
    Rydman, RJ
    Landay, AL
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 1999, 15 (07) : 665 - 670
  • [40] IL-15 induces CD69 expression on peripheral blood lymphocytes and supports continuous CD69 upregulated expression on synovial fluid lymphocytes.
    Ortiz, AM
    Garcia-Vicuña, R
    Sancho, D
    Vicente, E
    Sabando, P
    González-Alvaro, I
    ARTHRITIS AND RHEUMATISM, 1998, 41 (09): : S35 - S35
12345