Antifungal dosing in critically ill patients

被引:1
|
作者
Bergman S.J. [1 ]
Tyagi I. [1 ]
Ronald K. [1 ]
机构
[1] Division of Infectious Diseases, Southern Illinois University School of Medicine, Springfield, IL 62794, 701 North 1st Street
关键词
Amphotericin B; Anidulafungin; Antifungals; Caspofungin; Combinations; Critical care; Dose; Echinocandin; Fluconazole; Flucytosine; ICU; Itraconazole; Lipid formulations; Micafungin; Pharmacodynamics; Pharmacokinetics; Posaconazole; Triazole; Voriconazole;
D O I
10.1007/s12281-010-0012-z
中图分类号
学科分类号
摘要
This article reviews appropriate dosing for antifungals and emphasizes factors specific to the critically ill patient, along with drug pharmacokinetics and pharmacodynamics. The rationale for doses of the echinocandins (caspofungin, micafungin, anidulafungin), triazoles (fluconazole, voriconazole, itraconazole, posaconazole), amphotericin B (including lipid formulations), and flucytosine are discussed. © 2010 Springer Science+Business Media, LLC.
引用
收藏
页码:78 / 86
页数:8
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