In silico prediction of novel therapeutic targets using gene–disease association data

被引：0
|
作者：
Enrico Ferrero
Ian Dunham
Philippe Sanseau
机构：
[1] GSK Medicines Research Centre,Computational Biology and Stats, Target Sciences
[2] European Bioinformatics Institute (EMBL-EBI),European Molecular Biology Laboratory
[3] Open Targets,undefined
来源：
Journal of Translational Medicine | / 15卷
关键词：
Drug discovery; Target discovery; Gene–disease associations; Machine learning; Data mining;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Prediction of antipsychotics gene targets by integration of genomic, evolutionary, and gene expression data
    Ambesi-Impiombato, A.
    Panariello, F.
    de Bartolomeis, A.
    Muscettola, G.
    EUROPEAN PSYCHIATRY, 2007, 22 : S146 - S147
  • [42] Current and novel therapeutic molecules and targets in Alzheimer's disease
    Kumar, Ashwini
    Nisha, Chaluveelaveedu Murleedharan
    Silakari, Chitrangda
    Sharma, Isha
    Anusha, Kanukanti
    Gupta, Nityasha
    Nair, Prateek
    Tripathi, Timir
    Kumar, Awanish
    JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 2016, 115 (01) : 3 - 10
  • [43] Epigenetic modifications as novel therapeutic targets for Huntington's disease
    Wang, Fengli
    Fischhaber, Paula L.
    Guo, Caixia
    Tang, Tie-Shan
    EPIGENOMICS, 2014, 6 (03) : 287 - 297
  • [44] α-Synuclein Ubiquitination and Novel Therapeutic Targets for Parkinson's Disease
    Rott, Ruth
    Szargel, Raymonde
    Shani, Vered
    Bisharat, Sleman
    Engelender, Simone
    CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2014, 13 (04) : 630 - 637
  • [45] GROWTH-FACTORS AS NOVEL THERAPEUTIC TARGETS IN NEOPLASTIC DISEASE
    GREIG, R
    DUNNINGTON, D
    MURTHY, U
    ANZANO, M
    CANCER SURVEYS, 1988, 7 (04) : 653 - 674
  • [46] Novel therapeutic targets of metformin: metabolic syndrome and cardiovascular disease
    Ladeiras-Lopes, Ricardo
    Fontes-Carvalho, Ricardo
    Bettencourt, Nuno
    Sampaio, Francisco
    Gama, Vasco
    Leite-Moreira, Adelino
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2015, 19 (07) : 869 - 877
  • [47] The genetic background of Parkinson's disease and novel therapeutic targets
    Salamon, Andras
    Zadori, Denes
    Szpisjak, Laszlo
    Klivenyi, Peter
    Vecsei, Laszlo
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2022, 26 (10) : 827 - 836
  • [48] Microparticles as Novel Biomarkers and Therapeutic Targets in Coronary Heart Disease
    Zhou Bo-Da
    Guo Ge
    Zheng Le-Min
    Zu Ling-Yun
    Gao Wei
    中华医学杂志英文版, 2015, 128 (02) : 267 - 272
  • [49] Microparticles as Novel Biomarkers and Therapeutic Targets in Coronary Heart Disease
    Zhou, Bo-Da
    Guo, Ge
    Zheng, Le-Min
    Zu, Ling-Yun
    Gao, Wei
    CHINESE MEDICAL JOURNAL, 2015, 128 (02) : 267 - 272
  • [50] Comprehensive Integration of Genome-Wide Association and Gene Expression Studies Reveals Novel Gene Signatures and Potential Therapeutic Targets for Helicobacter pylori-Induced Gastric Disease
    Badr, Mohamed Tarek
    Omar, Mohamed
    Hacker, Georg
    FRONTIERS IN IMMUNOLOGY, 2021, 12
12345